Methyldopa and Theophyl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Methyldopa (methyldopa) and Theophyl (theophylline). Common drug interactions include diabetic neuropathy among females and hypotension among males.

The phase IV clinical study analyzes what interactions people have when they take Methyldopa and Theophyl. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Methyldopa?

Methyldopa has active ingredients of methyldopa. It is often used in high blood pressure. eHealthMe is studying from 6,475 Methyldopa users. Check the latest studies of Methyldopa.

What is Theophyl?

Theophyl has active ingredients of theophylline. eHealthMe is studying from 19,174 Theophyl users. Check the latest studies of Theophyl.

On Jul, 12, 2026

24 people who take Methyldopa and Theophyl together, and have interactions are studied.

Methyldopa and Theophyl drug interactions.

What are the common drug interactions of Methyldopa and Theophyl, by gender? *:

female:

Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Dizziness
Dry mouth
Duodenitis (inflammation of the duodenum)
Dysarthria (speech disorder)
Dysphagia (a condition in which swallowing is difficult or painful)
Dystonia (abnormal muscle tone)
Early satiety (feeling full before completing a normal sized meal)
Epistaxis (bleed from the nose)
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)

male:

Hypotension (abnormally low blood pressure)
Polyuria (production of too much dilute urine)
Blood creatine phosphokinase increased
Body temperature decreased
Cardiac arrest
Cerebral infarction (less blood supply to brain resulting tissue damage)
Depressed level of consciousness
Depression
Hemiplegia (paralysis of one side of the body)
Insomnia (sleeplessness)

What are the common drug interactions of Methyldopa and Theophyl, by age (0-1 to 60+)? *:

0-1:

Hypotonia neonatal (low muscle tone in neonatal)
Proptosis
Psychomotor retardation (motor mental retardation)

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Alopecia (absence of hair from areas of the body)
Asthma
Body tinea (ringworm of the body)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Constipation
Dyspepsia (indigestion)
Gastritis (inflammation of stomach)
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Glossitis (infection of tongue with soreness)

40-49:

n/a

50-59:

Viral infection

60+:

Hypotension (abnormally low blood pressure)
Coma (state of unconsciousness lasting more than six hours)
Body temperature decreased
Cerebral infarction (less blood supply to brain resulting tissue damage)
Depressed level of consciousness
Depression
Hemiplegia (paralysis of one side of the body)
Insomnia (sleeplessness)
Pain
Renal failure acute (rapid kidney dysfunction)

What are the existing conditions these people have? *

Suicide Attempt: 5 people, 20.83%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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