Methylene blue and Rocuronium bromide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Methylene blue (methylene blue) and Rocuronium bromide (rocuronium bromide). Common drug interactions include serotonin syndrome among females and burkholderia test positive among males.

The phase IV clinical study analyzes what interactions people have when they take Methylene blue and Rocuronium bromide. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Methylene blue?

Methylene blue has active ingredients of methylene blue. eHealthMe is studying from 1,064 Methylene blue users. Check the latest studies of Methylene blue.

What is Rocuronium bromide?

Rocuronium bromide has active ingredients of rocuronium bromide. eHealthMe is studying from 5,615 Rocuronium bromide users. Check the latest studies of Rocuronium bromide.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

34 people who take Methylene blue and Rocuronium bromide together, and have interactions are studied.

Methylene blue and Rocuronium bromide drug interactions.

What are the common drug interactions of Methylene Blue and Rocuronium Bromide, by gender? *:

female:

Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Alanine aminotransferase increased
Amylase increased
Blood creatine phosphokinase increased
Blood lactate dehydrogenase increased
Blood potassium increased
Hypotension (abnormally low blood pressure)
Myoglobin urine present
Toxic encephalopathy (a degenerative neurologic disorder caused by exposure to toxic substances)
Troponin increased

male:

Burkholderia test positive
Respiratory rate decreased (less breathing rate/min)
Hyperhidrosis (abnormally increased sweating)
Insomnia (sleeplessness)
Myopathy (a muscular disease in which the muscle fibres do not function)
Obesity (having too much body fat)
Po2 decreased
Pyrexia (fever)
Restlessness (not able to rest)
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)

What are the common drug interactions of Methylene Blue and Rocuronium Bromide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Thrombocytopenia (decrease of platelets in blood)
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Cardiovascular disorder (heart diseases)
Abulia (lack of will or initiative)
Agitation (state of anxiety or nervous excitement)
Aphasia (damage to the parts of the brain that control language)
Blood glucose increased
Blood pressure systolic increased
Confusional state
Insomnia (sleeplessness)

40-49:

Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Alanine aminotransferase increased
Amylase increased
Blood creatine phosphokinase increased
Blood lactate dehydrogenase increased
Blood potassium increased
Hypotension (abnormally low blood pressure)
Myoglobin urine present
Toxic encephalopathy (a degenerative neurologic disorder caused by exposure to toxic substances)
Troponin increased

50-59:

n/a

60+:

Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Coma (state of unconsciousness lasting more than six hours)
Clonus (series of involuntary, rhythmic, muscular contractions and relaxations)
Confusional state
Dental caries
Device dislocation
Dyskinesia (abnormality or impairment of voluntary movement)
Dyspnoea (difficult or laboured respiration)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Fall

What are the existing conditions these people have? *

Depression: 17 people, 50.00%
Stress And Anxiety: 13 people, 38.24%
Hypotonia (low muscle tone): 11 people, 32.35%
Hypotension (abnormally low blood pressure): 11 people, 32.35%
Anaesthesia: 9 people, 26.47%
Vasoplegia Syndrome (low systemic vascular resistance): 4 people, 11.76%
Pain: 2 people, 5.88%
General Anaesthesia: 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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