Methylfolate and Fluconazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Methylfolate (folic acid) and Fluconazole (fluconazole). Common drug interactions include anxiety among females.

The phase IV clinical study analyzes what interactions people have when they take Methylfolate and Fluconazole. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Methylfolate?

Methylfolate has active ingredients of folic acid. eHealthMe is studying from 1,018 Methylfolate users. Check the latest studies of Methylfolate.

What is Fluconazole?

Fluconazole has active ingredients of fluconazole. It is often used in vaginal yeast infection. eHealthMe is studying from 70,481 Fluconazole users. Check the latest studies of Fluconazole.

On Aug, 06, 2026

21 people who take Methylfolate and Fluconazole together, and have interactions are studied.

Methylfolate and Fluconazole drug interactions.

What are the common drug interactions of Methylfolate and Fluconazole, by gender? *:

female:

Anxiety
Hypersensitivity
Haematoma (collection of blood outside the blood vessels)
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection)
Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone)
Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)
Sinusitis (inflammation of sinus)
Blood pressure increased
Migraine (headache)
Thrombosis (formation of a blood clot inside a blood vessel)

male:

n/a

What are the common drug interactions of Methylfolate and Fluconazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Hypersensitivity
Tendonitis (a condition that causes pain and swelling of tendons)
Anxiety
Depression
Pain

30-39:

n/a

40-49:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Respiratory disorder (respiratory disease)

50-59:

Anxiety
Balance disorder
Blood pressure increased
Dizziness
Feeling of body temperature change
Hypoaesthesia (reduced sense of touch or sensation)
Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)
Weight decreased

60+:

Asthenia (weakness)
Contusion (a type of hematoma of tissue in which capillaries)
Abdominal discomfort
Abdominal pain
Aphasia (damage to the parts of the brain that control language)
Arthralgia (joint pain)
Back pain
Bladder prolapse (bulging of one or more of the pelvic organs into the vagina)
Confusional state
Cyst (a closed sac)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 7 people, 33.33%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 23.81%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 23.81%
Migraine (headache): 4 people, 19.05%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 3 people, 14.29%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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