Methylfolate and Lunesta drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Methylfolate (folic acid) and Lunesta (eszopiclone). Common drug interactions include sinusitis among females.

The phase IV clinical study analyzes what interactions people have when they take Methylfolate and Lunesta. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Methylfolate?

Methylfolate has active ingredients of folic acid. eHealthMe is studying from 1,018 Methylfolate users. Check the latest studies of Methylfolate.

What is Lunesta?

Lunesta has active ingredients of eszopiclone. It is often used in insomnia. eHealthMe is studying from 26,936 Lunesta users. Check the latest studies of Lunesta.

On Jul, 31, 2026

40 people who take Methylfolate and Lunesta together, and have interactions are studied.

Methylfolate and Lunesta drug interactions.

What are the common drug interactions of Methylfolate and Lunesta, by gender? *:

female:

Sinusitis (inflammation of sinus)
Injection site pain
Agitation (state of anxiety or nervous excitement)
Cerebral disorder (brain disease)
Daydreaming
Feeling hot
General physical health deterioration (weak health status)
Mania (a state of abnormally elevated or irritable mood)
Memory impairment
Neurotransmitter level altered

male:

n/a

What are the common drug interactions of Methylfolate and Lunesta, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Drug dependence
Eyelid ptosis (falling of the upper or lower eyelid)
Yawning (simultaneous inhalation of air and stretching of the eardrums, followed by exhalation of breath)
Agitation (state of anxiety or nervous excitement)
Cerebral disorder (brain disease)
Daydreaming
Feeling hot
General physical health deterioration (weak health status)
Headache (pain in head)
Mania (a state of abnormally elevated or irritable mood)

40-49:

Middle ear effusion (fluid in middle ear)
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Respiratory tract infection viral
Urinary tract infection
Weight decreased
Anal fissure
Erythema (redness of the skin)
Influenza
Infusion site mass
Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)

50-59:

Amyotrophic lateral sclerosis (nervous system disease that attacks nerve cells called neurons in your brain and spinal cord)
Blood immunoglobulin g increased
Gait disturbance
Immunodeficiency
Lymphocyte count increased
Muscular weakness (muscle weakness)
Apathy
Asthenia (weakness)
Atrophy (wasting away of a part of the body)
Balance disorder

60+:

Sinusitis (inflammation of sinus)
Oedema (fluid collection in tissue)
Pyrexia (fever)
Rash pruritic (redness with itching)
Abdominal discomfort
Abdominal pain
Anxiety
Aphasia (damage to the parts of the brain that control language)
Arthralgia (joint pain)
Back pain

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 12 people, 30.00%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 12.50%
Depression: 5 people, 12.50%
Sleep Disorder: 5 people, 12.50%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 4 people, 10.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 7.50%
Mood Swings (an extreme or rapid change in mood): 3 people, 7.50%
Migraine (headache): 3 people, 7.50%
Memory Loss: 3 people, 7.50%
Injury: 3 people, 7.50%

* Approximation only. Some reports may have incomplete information.

Do you take Methylfolate and Lunesta?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously