Methylphenidate and Duopa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Methylphenidate (methylphenidate) and Duopa (carbidopa; levodopa). Common drug interactions include dizziness among females and fall among males.

The phase IV clinical study analyzes what interactions people have when they take Methylphenidate and Duopa. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Methylphenidate?

Methylphenidate has active ingredients of methylphenidate. eHealthMe is studying from 8,216 Methylphenidate users. Check the latest studies of Methylphenidate.

What is Duopa?

Duopa has active ingredients of carbidopa; levodopa. eHealthMe is studying from 8,208 Duopa users. Check the latest studies of Duopa.

On Jul, 07, 2026

12 people who take Methylphenidate and Duopa together, and have interactions are studied.

Methylphenidate and Duopa drug interactions.

What are the common drug interactions of Methylphenidate and Duopa, by gender? *:

female:

Dizziness
Urinary tract infection
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Arthropathy
Death
Fall
Hip fracture

male:

Fall
Hypertension (high blood pressure)
Unresponsive to stimuli
Asthenia (weakness)
Dyspnoea (difficult or laboured respiration)
On and off phenomenon
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood pressure decreased
Fatigue (feeling of tiredness)
Loss of consciousness

What are the common drug interactions of Methylphenidate and Duopa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Urinary tract infection
Death
Hyperkalaemia (damage to or disease of the kidney)
Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate)
Dizziness
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Arthropathy
Fall
Hip fracture
Terminal state (the transitional states between life and biological death)

What are the existing conditions these people have? *

Parkinson's Disease: 8 people, 66.67%
High Blood Pressure: 4 people, 33.33%
Sleep Disorder: 3 people, 25.00%
Vision Blurred: 2 people, 16.67%
Urinary Tract Disorder: 2 people, 16.67%
Stress And Anxiety: 2 people, 16.67%
Neuropathy Peripheral (surface nerve damage): 2 people, 16.67%
Diarrhea: 2 people, 16.67%
Depression: 2 people, 16.67%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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