Methylphenidate and Neupro drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Methylphenidate (methylphenidate) and Neupro (rotigotine). Common drug interactions include anaphylactic reaction among females and balance disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Methylphenidate and Neupro. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Methylphenidate?

Methylphenidate has active ingredients of methylphenidate. eHealthMe is studying from 8,217 Methylphenidate users. Check the latest studies of Methylphenidate.

What is Neupro?

Neupro has active ingredients of rotigotine. It is often used in parkinson's disease. eHealthMe is studying from 11,393 Neupro users. Check the latest studies of Neupro.

On Aug, 13, 2026

18 people who take Methylphenidate and Neupro together, and have interactions are studied.

Methylphenidate and Neupro drug interactions.

What are the common drug interactions of Methylphenidate and Neupro, by gender? *:

female:

Anaphylactic reaction (serious allergic reaction)
Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
Cystitis (inflammation of the wall of the bladder)
Acne (skin problems that cause pimples)
Anxiety
Blood pressure increased
Dyspnoea (difficult or laboured respiration)
Nasopharyngitis (inflammation of the nasopharynx)
Nausea (feeling of having an urge to vomit)
Blood pressure decreased

male:

Balance disorder
Bruxism (habitual grinding of the teeth, typically during sleep)
Tooth extraction
Tooth infection
Toothache (tooth pain)
Constipation
Fluid retention (an abnormal accumulation of fluid in the blood)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hallucination (an experience involving the perception of something not present)

What are the common drug interactions of Methylphenidate and Neupro, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Muscle spasms (muscle contraction)
Surgery

60+:

Anaphylactic reaction (serious allergic reaction)
Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
Infection
Somnolence (a state of near-sleep, a strong desire for sleep)
Tooth extraction
Tooth infection
Toothache (tooth pain)
Asthenia (weakness)
Constipation
Dizziness

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 16 people, 88.89%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 44.44%
Drowsiness: 3 people, 16.67%
Pain: 2 people, 11.11%
Restless Leg Syndrome (a powerful urge to move your legs): 1 person, 5.56%
Cough: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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