Metoclopramide hcl and Aprepitant drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Metoclopramide hcl (metoclopramide hydrochloride) and Aprepitant (aprepitant). Common drug interactions include neutropenia among females and neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Metoclopramide hcl and Aprepitant. It is created by eHealthMe based on reports of 81 people who take the same drugs from the FDA, and is updated regularly.

What is Metoclopramide hcl?

Metoclopramide hcl has active ingredients of metoclopramide hydrochloride. It is often used in nausea and vomiting. eHealthMe is studying from 2,459 Metoclopramide hcl users. Check the latest studies of Metoclopramide hcl.

What is Aprepitant?

Aprepitant has active ingredients of aprepitant. eHealthMe is studying from 6,992 Aprepitant users. Check the latest studies of Aprepitant.

On Jul, 09, 2026

81 people who take Metoclopramide hcl and Aprepitant together, and have interactions are studied.

Metoclopramide hcl and Aprepitant drug interactions.

What are the common drug interactions of Metoclopramide Hcl and Aprepitant, by gender? *:

female:

Neutropenia (an abnormally low number of neutrophils)
Febrile neutropenia (fever with reduced white blood cells)
Panic disorder
Anaemia (lack of blood)
Dehydration (dryness resulting from the removal of water)
Haemolytic anaemia (anaemia due to haemolysis)
Presyncope
Acute respiratory failure
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)

male:

Neutropenia (an abnormally low number of neutrophils)
Pyrexia (fever)
Cataract (clouding of the lens inside the eye)
Dehydration (dryness resulting from the removal of water)
Device related infection
Diarrhoea
Dizziness
Enterocolitis infectious
Fatigue (feeling of tiredness)
Glucose urine present

What are the common drug interactions of Metoclopramide Hcl and Aprepitant, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Presyncope

20-29:

n/a

30-39:

Anaemia (lack of blood)
Febrile neutropenia (fever with reduced white blood cells)
Dehydration (dryness resulting from the removal of water)
Haemolytic anaemia (anaemia due to haemolysis)
Diarrhoea
Dizziness
Fatigue (feeling of tiredness)
Mouth ulceration (mouth ulcers)
Stomatitis (inflammation of mucous membrane of mouth)
Abdominal pain

40-49:

Neutropenia (an abnormally low number of neutrophils)
Febrile neutropenia (fever with reduced white blood cells)

50-59:

Neutropenia (an abnormally low number of neutrophils)
Febrile neutropenia (fever with reduced white blood cells)
Blood sodium decreased
Blood urine present
Dehydration (dryness resulting from the removal of water)
Device related infection
Enterocolitis infectious
Glucose urine present
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Hypokalaemia (low potassium)

60+:

Neutropenia (an abnormally low number of neutrophils)
Respiratory tract infection
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Platelet count decreased
Speech disorder
Urinary tract infection
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Infection

What are the existing conditions these people have? *

Febrile Neutropenia (fever with reduced white blood cells): 46 people, 56.79%
Breast Cancer: 11 people, 13.58%
Lung Cancer - Non-Small Cell (lung cancer): 10 people, 12.35%
Nausea And Vomiting: 7 people, 8.64%
Pain: 5 people, 6.17%
Diarrhea: 5 people, 6.17%

* Approximation only. Some reports may have incomplete information.

Do you take Metoclopramide hcl and Aprepitant?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously