Metoclopramide and Invokamet drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Metoclopramide (metoclopramide hydrochloride) and Invokamet (canagliflozin; metformin hydrochloride). Common drug interactions include chronic kidney disease among females and spinal compression fracture among males.

The phase IV clinical study analyzes what interactions people have when they take Metoclopramide and Invokamet. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Metoclopramide?

Metoclopramide has active ingredients of metoclopramide hydrochloride. It is often used in nausea. eHealthMe is studying from 81,263 Metoclopramide users. Check the latest studies of Metoclopramide.

What is Invokamet?

Invokamet has active ingredients of canagliflozin; metformin hydrochloride. eHealthMe is studying from 1,965 Invokamet users. Check the latest studies of Invokamet.

On Jul, 14, 2026

11 people who take Metoclopramide and Invokamet together, and have interactions are studied.

Metoclopramide and Invokamet drug interactions.

What are the common drug interactions of Metoclopramide and Invokamet, by gender? *:

female:

Chronic kidney disease
Renal failure (kidney dysfunction)
Diarrhoea
Impaired gastric emptying

male:

Spinal compression fracture (fracture due to spinal compression on bone)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Multiple fractures
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Pain
Quality of life decreased
Foot fracture
Spinal fracture (fracture in one of vertebrae)
Anxiety

What are the common drug interactions of Metoclopramide and Invokamet, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Diarrhoea
Impaired gastric emptying

50-59:

Spinal compression fracture (fracture due to spinal compression on bone)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Multiple fractures
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Pain
Quality of life decreased
Foot fracture
Spinal fracture (fracture in one of vertebrae)
Anxiety

60+:

n/a

What are the existing conditions these people have? *

Pain: 10 people, 90.91%
Diabetes: 10 people, 90.91%
Fungal Infection: 9 people, 81.82%
Stress And Anxiety: 9 people, 81.82%
Depression: 9 people, 81.82%
High Blood Pressure: 9 people, 81.82%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 9 people, 81.82%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 81.82%
Inflammation: 9 people, 81.82%
High Blood Cholesterol: 6 people, 54.55%

* Approximation only. Some reports may have incomplete information.

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