Metoprolol succinate and Relistor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Metoprolol succinate (metoprolol succinate) and Relistor (methylnaltrexone bromide). Common drug interactions include pain among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Metoprolol succinate and Relistor. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Metoprolol succinate?

Metoprolol succinate has active ingredients of metoprolol succinate. It is often used in high blood pressure. eHealthMe is studying from 66,933 Metoprolol succinate users. Check the latest studies of Metoprolol succinate.

What is Relistor?

Relistor has active ingredients of methylnaltrexone bromide. eHealthMe is studying from 1,659 Relistor users. Check the latest studies of Relistor.

On Aug, 06, 2026

18 people who take Metoprolol succinate and Relistor together, and have interactions are studied.

Metoprolol succinate and Relistor drug interactions.

What are the common drug interactions of Metoprolol Succinate and Relistor, by gender? *:

female:

Pain
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Aphasia (damage to the parts of the brain that control language)
Blood sodium decreased
Crying
Gait disturbance
Nausea (feeling of having an urge to vomit)
Affect lability (emotional incontinence)
Back pain
Blood pressure fluctuation

male:

Arthralgia (joint pain)
Abdominal distension
Back pain
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Benign prostatic hyperplasia (benign enlargement of the prostate)
Bone disorder
Bone pain
Cardiac disorder
Cerebral small vessel ischaemic disease (inadequate blood supply to small blood vessel of brain)
Chest pain

What are the common drug interactions of Metoprolol Succinate and Relistor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Constipation
Diarrhoea
Dizziness
Dry mouth
Ear infection
Eye swelling
Flushing (the warm, red condition of human skin)
Nausea (feeling of having an urge to vomit)
Pain
Vomiting

50-59:

Mouth ulceration (mouth ulcers)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Myopia (difficult to see objects that are far away)
Nasal obstruction (blockage of nose)
Nasal septum deviation (deviated nasal septum)
Nasal turbinate hypertrophy (nasal turbinates become enlarged)
Neoplasm malignant (cancer tumour)
Neoplasm progression (growth of tumour)
Nephrolithiasis (calculi in the kidneys)
Neuralgia (pain in one or more nerves)

60+:

Fall
Abdominal pain
Decreased appetite
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dyspnoea (difficult or laboured respiration)
Escherichia bacteraemia (presence of bacteria escherichia coli in the blood)
Faeces discoloured
Failure to thrive (inadequate weight gain and physical growth in children)
Fungal infection
Generalised oedema (swelling all over the body)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 50.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 44.44%
Multiple Myeloma (cancer of the plasma cells): 2 people, 11.11%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 5.56%
Pancreatic Carcinoma (pancreatic cancer): 1 person, 5.56%
Ovarian Cancer (cancer of ovary): 1 person, 5.56%
Metastases To Bone (cancer spreads to bone): 1 person, 5.56%
Gout (uric acid crystals building up in the body): 1 person, 5.56%
Dyslipidaemia (abnormal amount of lipids): 1 person, 5.56%
Drowsiness: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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