Metrolotion and Macrobid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Metrolotion (metronidazole) and Macrobid (nitrofurantoin; nitrofurantoin, macrocrystalline). Common drug interactions include aortic arteriosclerosis among females and scar among males.

The phase IV clinical study analyzes what interactions people have when they take Metrolotion and Macrobid. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Metrolotion?

Metrolotion has active ingredients of metronidazole. eHealthMe is studying from 127 Metrolotion users. Check the latest studies of Metrolotion.

What is Macrobid?

Macrobid has active ingredients of nitrofurantoin; nitrofurantoin, macrocrystalline. It is often used in urinary tract infection. eHealthMe is studying from 9,215 Macrobid users. Check the latest studies of Macrobid.

On Jul, 08, 2026

24 people who take Metrolotion and Macrobid together, and have interactions are studied.

Metrolotion and Macrobid drug interactions.

What are the common drug interactions of Metrolotion and Macrobid, by gender? *:

female:

Aortic arteriosclerosis (hardening of the aortic arteries)
Diarrhoea
Discomfort
Dry mouth
Dysphonia (speech disorder attributable to a disorder of phonation)
Dyspnoea (difficult or laboured respiration)
Emotional distress
Fall
Feeling jittery
Fractured sacrum

male:

Scar
Acute sinusitis
Bone loss
Candidiasis (candidiasis or thrush is a fungal infection)
Cellulitis (infection under the skin)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Constipation
Contusion (a type of hematoma of tissue in which capillaries)
Decreased appetite

What are the common drug interactions of Metrolotion and Macrobid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Arthropathy
Back pain
Bone disorder
Bone loss
Candidiasis (candidiasis or thrush is a fungal infection)
Cellulitis (infection under the skin)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Constipation
Contusion (a type of hematoma of tissue in which capillaries)

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Feeling jittery
Fractured sacrum
Gingival bleeding (bleeding gums)
Heart rate increased
Heart rate irregular
Hypophagia (reduced food intake)
Influenza
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 24 people, 100.00%

* Approximation only. Some reports may have incomplete information.

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