Metronidazole and Vasotec drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Metronidazole (metronidazole) and Vasotec (enalapril maleate). Common drug interactions include decreased appetite among females and renal cyst among males.

The phase IV clinical study analyzes what interactions people have when they take Metronidazole and Vasotec. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Metronidazole?

Metronidazole has active ingredients of metronidazole. It is often used in vaginitis bacterial. eHealthMe is studying from 59,578 Metronidazole users. Check the latest studies of Metronidazole.

What is Vasotec?

Vasotec has active ingredients of enalapril maleate. It is often used in high blood pressure. eHealthMe is studying from 14,646 Vasotec users. Check the latest studies of Vasotec.

On Jul, 05, 2026

46 people who take Metronidazole and Vasotec together, and have interactions are studied.

Metronidazole and Vasotec drug interactions.

What are the common drug interactions of Metronidazole and Vasotec, by gender? *:

female:

Decreased appetite
Diarrhoea
Oedema (fluid collection in tissue)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Back pain
Constipation
Fall
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hypoaesthesia (reduced sense of touch or sensation)
Intervertebral disc protrusion (spinal disc protrusion)

male:

Renal cyst (kidney cyst)
Renal failure (kidney dysfunction)
Diarrhoea
Gout (uric acid crystals building up in the body)
Haematoma (collection of blood outside the blood vessels)
Heart injury
Hypotension (abnormally low blood pressure)
Hypovolaemia (a decreased volume of circulating blood in the body)
Multiple injuries
Pain

What are the common drug interactions of Metronidazole and Vasotec, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Pain
Dry skin
Extremity contracture (permanent shortening of a muscle or joint of arms and legs)
Hyperkeratosis (thickening of the outer layer of the skin)
Mobility decreased (ability to move is reduced)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Oedema (fluid collection in tissue)
Peripheral ischaemia (impaired circulation to an extremity)
Peroneal nerve palsy
Skin depigmentation (lightening of the skin)

30-39:

Difficulty in walking
Hypoaesthesia (reduced sense of touch or sensation)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

40-49:

Cardiomegaly (increased size of heart than normal)
Depressed level of consciousness
Fatigue (feeling of tiredness)
Headache (pain in head)
Metabolic disorder (an abnormal function and pattern of body fat. insulin resistance refers to the diminished ability of cells to respond to the action of insulin in promoting the transport of the sugar glucose, from blood into muscles and other tissues)
Proteus infection (proteus can cause urinary tract infections)
Pulmonary oedema (fluid accumulation in the lungs)
Renal failure (kidney dysfunction)
Sore throat (pain or irritation of the throat)
Urinary tract infection

50-59:

Dyslipidaemia (abnormal amount of lipids)
Gout (uric acid crystals building up in the body)
Hypokalaemia (low potassium)
Intermittent claudication
Nephritis (inflammation of the nephrons in the kidneys)
Renal impairment (severely reduced kidney function)
Staphylococcal infection (an infection with staphylococcus bacteria)
Chronic kidney disease
Renal cyst (kidney cyst)
Renal failure (kidney dysfunction)

60+:

Diarrhoea
General physical health deterioration (weak health status)
Constipation
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hypoaesthesia (reduced sense of touch or sensation)
Infection
Intervertebral disc protrusion (spinal disc protrusion)
Neuropathy peripheral (surface nerve damage)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Spinal column stenosis (narrowing of spinal column)

What are the existing conditions these people have? *

Nuclear Magnetic Resonance Imaging Brain: 8 people, 17.39%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 6.52%

* Approximation only. Some reports may have incomplete information.

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