Mexitil and Gemzar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mexitil (mexiletine hydrochloride) and Gemzar (gemcitabine hydrochloride). Common drug interactions include cystitis among females and respiratory failure among males.

The phase IV clinical study analyzes what interactions people have when they take Mexitil and Gemzar. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Mexitil?

Mexitil has active ingredients of mexiletine hydrochloride. eHealthMe is studying from 1,893 Mexitil users. Check the latest studies of Mexitil.

What is Gemzar?

Gemzar has active ingredients of gemcitabine hydrochloride. It is often used in pancreatic carcinoma. eHealthMe is studying from 20,315 Gemzar users. Check the latest studies of Gemzar.

On Aug, 01, 2026

22 people who take Mexitil and Gemzar together, and have interactions are studied.

What are the common drug interactions of Mexitil and Gemzar, by gender? *:

female:

Cystitis (inflammation of the wall of the bladder)
Delirium (wild excitement)
Gastric ulcer (stomach ulcer)
Hyperkalaemia (damage to or disease of the kidney)
Neurogenic bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion)
Pyelonephritis (inflammation of kidney caused by bacteria)
Drug hypersensitivity
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Erythema (redness of the skin)
Pruritus (severe itching of the skin)

male:

Respiratory failure (inadequate gas exchange by the respiratory system)
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Pulmonary congestion (congestion in the lungs)
Pyrexia (fever)
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
Anaemia (lack of blood)
Depressed level of consciousness
Disease progression
Electrocardiogram qt prolonged
Excitability

What are the common drug interactions of Mexitil and Gemzar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Anaemia (lack of blood)
Pleural effusion (water on the lungs)
Pyrexia (fever)
Respiratory disorder (respiratory disease)
Respiratory failure (inadequate gas exchange by the respiratory system)
Cancer pain
Disease progression
Gastric ulcer (stomach ulcer)
Gastric ulcer haemorrhage (bleeding ulcer of stomach)
Haematemesis (vomiting of blood)

60+:

Cystitis (inflammation of the wall of the bladder)
Delirium (wild excitement)
Pruritus (severe itching of the skin)
Rash
Rash pruritic (redness with itching)
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Cardiac failure
Cardiomegaly (increased size of heart than normal)
Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)

What are the existing conditions these people have? *

Cancer Pain: 8 people, 36.36%
Lung Cancer - Non-Small Cell (lung cancer): 5 people, 22.73%
Pleural Mesothelioma Malignant (cancer of the pleura, or the membrane that lines the lungs): 4 people, 18.18%
Chest Pain: 4 people, 18.18%
Malignant Neoplasm Of Renal Pelvis (cancer tumour of ureter): 3 people, 13.64%
Kidney Infection (Pyelonephritis): 3 people, 13.64%
Diabetes: 2 people, 9.09%
Cardiac Failure: 2 people, 9.09%
Basedow's Disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones): 2 people, 9.09%
Adenocarcinoma Pancreas (cancer of pancreas): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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