Mexitil and Meropenem drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mexitil (mexiletine hydrochloride) and Meropenem (meropenem). Common drug interactions include epistaxis among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Mexitil and Meropenem. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Mexitil?

Mexitil has active ingredients of mexiletine hydrochloride. eHealthMe is studying from 1,893 Mexitil users. Check the latest studies of Mexitil.

What is Meropenem?

Meropenem has active ingredients of meropenem. eHealthMe is studying from 33,295 Meropenem users. Check the latest studies of Meropenem.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

12 people who take Mexitil and Meropenem together, and have interactions are studied.

Mexitil and Meropenem drug interactions.

What are the common drug interactions of Mexitil and Meropenem, by gender? *:

female:

Epistaxis (bleed from the nose)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Thrombocytopenia (decrease of platelets in blood)
White blood cell count decreased
International normalised ratio increased
Sepsis (a severe blood infection that can lead to organ failure and death)
Abdominal pain
Infection
Pain in extremity

male:

Renal failure (kidney dysfunction)
Blood creatinine increased
Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Renal impairment (severely reduced kidney function)
Sepsis (a severe blood infection that can lead to organ failure and death)
Vomiting
Arrhythmia (irregular heartbeat)
Blood lactate dehydrogenase increased
Blood uric acid increased

What are the common drug interactions of Mexitil and Meropenem, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

C-reactive protein increased
Fungaemia (fungi circulate in the blood)
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
Sepsis (a severe blood infection that can lead to organ failure and death)

60+:

Renal failure (kidney dysfunction)
Blood creatinine increased
Hyperkalaemia (damage to or disease of the kidney)
Hypertension (high blood pressure)
Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles)
Infection
International normalised ratio increased
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Renal impairment (severely reduced kidney function)

What are the existing conditions these people have? *

High Blood Pressure: 8 people, 66.67%
Arrhythmias (irregular heartbeat): 4 people, 33.33%
Sepsis (a severe blood infection that can lead to organ failure and death): 3 people, 25.00%
Constipation: 3 people, 25.00%
Multiple Myeloma (cancer of the plasma cells): 3 people, 25.00%
Gastritis (inflammation of stomach): 2 people, 16.67%
Cancer Pain: 2 people, 16.67%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 2 people, 16.67%
Insomnia (sleeplessness): 2 people, 16.67%
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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