Micronase and Sinemet drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Micronase (glyburide) and Sinemet (carbidopa; levodopa). Common drug interactions include atrial fibrillation among females and hypotension among males.

The phase IV clinical study analyzes what interactions people have when they take Micronase and Sinemet. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Micronase?

Micronase has active ingredients of glyburide. eHealthMe is studying from 1,922 Micronase users. Check the latest studies of Micronase.

What is Sinemet?

Sinemet has active ingredients of carbidopa; levodopa. It is often used in parkinson's disease. eHealthMe is studying from 29,601 Sinemet users. Check the latest studies of Sinemet.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 15, 2026

13 people who take Micronase and Sinemet together, and have interactions are studied.

Micronase and Sinemet drug interactions.

What are the common drug interactions of Micronase and Sinemet, by gender? *:

female:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Autonomic nervous system imbalance (autonomic nervous system is of net equal emphasis)
Balance disorder
Cardiac failure congestive
Cardiac murmur (an heart sound in valve abnormality)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cerebrovascular insufficiency (insufficient blood supply to brain)
Chest pain
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)

male:

Hypotension (abnormally low blood pressure)
Arthralgia (joint pain)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Intestinal obstruction
Loss of consciousness
Oesophagitis (inflammation of oesophagus)
Platelet count decreased
Pleural effusion (water on the lungs)
Sedation
Weakness

What are the common drug interactions of Micronase and Sinemet, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Hyperglycaemic hyperosmolar nonketotic syndrome (too much sugar (glucose) in your blood)
Neuropathy peripheral (surface nerve damage)
Type 1 diabetes mellitus
Diabetes mellitus inadequate control
Diabetic foot
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Hyperglycaemia (high blood sugar)

50-59:

Weight decreased

60+:

Cardiac failure congestive
Pleural effusion (water on the lungs)
Urinary tract infection
Vomiting
Weakness
Abdominal discomfort
Activated partial thromboplastin time prolonged
Acute myocardial infarction (acute heart attack)
Aggression
Ammonia increased

What are the existing conditions these people have? *

Stress And Anxiety: 2 people, 15.38%
Sleep Disorder: 2 people, 15.38%
Panic Disorder: 1 person, 7.69%
Hypersensitivity: 1 person, 7.69%
Headache (pain in head): 1 person, 7.69%
Hallucinations (sensations that appear real but are created by your mind): 1 person, 7.69%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.69%
Delusion (a false belief or opinion): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Micronase and Sinemet?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously