Midodrine hydrochloride and Claritin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Midodrine hydrochloride (midodrine hydrochloride) and Claritin (loratadine). Common drug interactions include cardiac arrest among females and device failure among males.
The phase IV clinical study analyzes what interactions people have when they take Midodrine hydrochloride and Claritin. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.
What is Midodrine hydrochloride?
Midodrine hydrochloride has active ingredients of midodrine hydrochloride. It is often used in hypotension. eHealthMe is studying from 3,274 Midodrine hydrochloride users. Check the latest studies of Midodrine hydrochloride.
What is Claritin?
Claritin has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 77,315 Claritin users. Check the latest studies of Claritin.
43 people who take Midodrine hydrochloride and Claritin together, and have interactions are studied.

What are the common drug interactions of Midodrine Hydrochloride and Claritin, by gender? *:
female:
- Cardiac arrest
- Cardiac failure congestive
- Chronic gastritis (long lasting infection of stomach lining)
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
- Death
- Device dislocation
- Dilatation ventricular
- Disease recurrence
- Dizziness
male:
- Device failure
- Asthenia (weakness)
- Peritonitis bacterial (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs by bacterial)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Abdominal discomfort
- Abdominal pain
- Abnormal loss of weight
- Anxiety
- Balance disorder
- Brain injury
What are the common drug interactions of Midodrine Hydrochloride and Claritin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Abdominal discomfort
- Abnormal loss of weight
- Dizziness
- Drug ineffective
- Dyspnoea (difficult or laboured respiration)
- Heart rate increased
- Nausea (feeling of having an urge to vomit)
20-29:
- Cardiac arrest
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
- Dysphagia (a condition in which swallowing is difficult or painful)
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Glossodynia (a burning or painful sensation in the tongue)
- Headache (pain in head)
- Loss of consciousness
- Palpitations (feelings or sensations that your heart is pounding or racing)
30-39:
- Abdominal pain
- Cellulitis (infection under the skin)
- Chronic kidney disease
- Cystitis (inflammation of the wall of the bladder)
- Fall
- Fatigue (feeling of tiredness)
- Haematoma (collection of blood outside the blood vessels)
- Headache (pain in head)
- Kidney infection
- Pain
40-49:
- Anxiety
- Chronic kidney disease
- Erythema (redness of the skin)
- Headache (pain in head)
- Nasopharyngitis (inflammation of the nasopharynx)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Renal failure (kidney dysfunction)
- Seasonal allergy (allergic condition due to certain season)
- Sputum discoloured
50-59:
- Nausea (feeling of having an urge to vomit)
- Abdominal distension
- Abdominal pain
- Arthralgia (joint pain)
- Arthrodesis
- Balance disorder
- Bone pain
- Burning sensation
- Constipation
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
60+:
- Asthenia (weakness)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Medical device complication
- Peritonitis bacterial (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs by bacterial)
- Respiratory disorder (respiratory disease)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Abdominal discomfort
- Acute respiratory failure
- Atelectasis (partial or complete collapse of the lung)
- Bladder cancer
What are the existing conditions these people have? *
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 9 people, 20.93%
- Immunodeficiency Common Variable: 5 people, 11.63%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 9.30%
- High Blood Cholesterol: 4 people, 9.30%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 9.30%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 6.98%
- Drowsiness: 3 people, 6.98%
* Approximation only. Some reports may have incomplete information.
Do you take Midodrine hydrochloride and Claritin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Midodrine hydrochloride (3,274 reports)
- Claritin (77,315 reports)
Browse all drug interactions of Midodrine hydrochloride and Claritin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Midodrine hydrochloride:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Claritin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Midodrine hydrochloride and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Claritin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on midodrine hydrochloride and loratadine (the active ingredients of Midodrine hydrochloride and Claritin, respectively), and Midodrine hydrochloride and Claritin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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