Milk thistle and Ditropan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Milk thistle (milk thistle) and Ditropan (oxybutynin chloride). Common drug interactions include gastrooesophageal reflux disease among females and hypoglycaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Milk thistle and Ditropan. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Milk thistle?

Milk thistle has active ingredients of milk thistle. It is often used in fatty liver. eHealthMe is studying from 5,057 Milk thistle users. Check the latest studies of Milk thistle.

What is Ditropan?

Ditropan has active ingredients of oxybutynin chloride. It is often used in urge incontinence. eHealthMe is studying from 11,799 Ditropan users. Check the latest studies of Ditropan.

On Jul, 24, 2026

17 people who take Milk thistle and Ditropan together, and have interactions are studied.

Milk thistle and Ditropan drug interactions.

What are the common drug interactions of Milk Thistle and Ditropan, by gender? *:

female:

Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Headache (pain in head)
Hypertension (high blood pressure)
Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate)
Jc virus infection
Post procedural infection
Shoulder operation
Application site pain
Arthralgia (joint pain)
Back pain

male:

Hypoglycaemia (deficiency of glucose in the bloodstream)
Syncope (loss of consciousness with an inability to maintain postural tone)

What are the common drug interactions of Milk Thistle and Ditropan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Cerebral disorder (brain disease)
White blood cell count decreased
Jc virus infection
Dry skin
Fatigue (feeling of tiredness)
Flushing (the warm, red condition of human skin)
Gait disturbance
Headache (pain in head)
Jc virus test positive

50-59:

Alopecia (absence of hair from areas of the body)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Colitis (inflammation of colon)
Diarrhoea
Fatigue (feeling of tiredness)
Flushing (the warm, red condition of human skin)
Headache (pain in head)
Hypersensitivity
Infection
Localised infection (infection at the single location)

60+:

Arthralgia (joint pain)
Back pain
Dysuria (painful or difficult urination)
Fatigue (feeling of tiredness)
Fracture
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hypertension (high blood pressure)
Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Insomnia (sleeplessness)

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 11 people, 64.71%
Gait Disturbance: 8 people, 47.06%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 11.76%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 11.76%
Urination - Painful: 1 person, 5.88%
Gastric Disorder (disease of stomach): 1 person, 5.88%
Amino Acid Metabolism Disorder: 1 person, 5.88%
Atrophic Vulvovaginitis (inflammation of the vulva): 1 person, 5.88%
Constipation: 1 person, 5.88%
Diabetes: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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