Minitran and Zide drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Minitran (nitroglycerin) and Zide (hydrochlorothiazide). Common drug interactions include neck pain among females and atrial flutter among males.
The phase IV clinical study analyzes what interactions people have when they take Minitran and Zide. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.
What is Minitran?
Minitran has active ingredients of nitroglycerin. eHealthMe is studying from 950 Minitran users. Check the latest studies of Minitran.
What is Zide?
Zide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 183,246 Zide users. Check the latest studies of Zide.
20 people who take Minitran and Zide together, and have interactions are studied.

What are the common drug interactions of Minitran and Zide, by gender? *:
female:
- Neck pain
- Nightmare (unpleasant dream)
- Odynophagia (painful swallowing, in the mouth (oropharynx) or oesophagus)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Chest pain
- Hypersensitivity
- Malignant neoplasm progression (cancer tumour came back)
- Pneumonitis (inflammation of the walls of the alveoli in the lungs)
- Respiratory tract infection
- Anxiety
male:
- Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
- Application site reaction
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Spinal vascular disorder (blood supply disease of spinal)
- Thrombotic stroke (stroke due to clot formation)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Burning sensation
- Diarrhoea
- Feeling jittery
- Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)
What are the common drug interactions of Minitran and Zide, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Rash
- Anxiety
- Biliary colic
- Decreased interest
- Diarrhoea
- Feeding disorder (when children refuse to eat certain food groups)
- Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
60+:
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Chest pain
- Respiratory tract infection
- Abdominal pain
- Affective disorder (mental disorder)
- Alopecia (absence of hair from areas of the body)
- Anaemia (lack of blood)
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Anxiety
- Application site reaction
What are the existing conditions these people have? *
- Lung Squamous Cell Carcinoma Stage Iii (lung cancer has spread to lymph nodes on the same side of the chest as the tumour. the lymph nodes with cancer are near the sternum (chest bone) or where the bronchus enters the lung): 4 people, 20.00%
- Type 2 Diabetes: 3 people, 15.00%
- Stable Angina (a constant chest pain): 3 people, 15.00%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 15.00%
- High Blood Cholesterol: 2 people, 10.00%
- Coronary Artery Insufficiency (insufficiency of artery to carry blood to heart): 2 people, 10.00%
- Cardiac Failure Congestive: 2 people, 10.00%
- Pulmonary Hypertension (increase in blood pressure in the lung artery): 1 person, 5.00%
- Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 1 person, 5.00%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 5.00%
* Approximation only. Some reports may have incomplete information.
Do you take Minitran and Zide?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Minitran and Zide:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Minitran:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Zide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Minitran and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on nitroglycerin and hydrochlorothiazide (the active ingredients of Minitran and Zide, respectively), and Minitran and Zide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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