Minivelle and Enbrel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Minivelle (estradiol) and Enbrel (etanercept). Common drug interactions include sinusitis among females and malaise among males.

The phase IV clinical study analyzes what interactions people have when they take Minivelle and Enbrel. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Minivelle?

Minivelle has active ingredients of estradiol. eHealthMe is studying from 3,480 Minivelle users. Check the latest studies of Minivelle.

What is Enbrel?

Enbrel has active ingredients of etanercept. It is often used in rheumatoid arthritis. eHealthMe is studying from 664,678 Enbrel users. Check the latest studies of Enbrel.

On Jul, 21, 2026

28 people who take Minivelle and Enbrel together, and have interactions are studied.

What are the common drug interactions of Minivelle and Enbrel, by gender? *:

female:

Sinusitis (inflammation of sinus)
Fall
Infusion related reaction
Migraine (headache)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Urticaria (rash of round, red welts on the skin that itch intensely)
Arthralgia (joint pain)
Asthenia (weakness)
Cardiac disorder
Dyspnoea (difficult or laboured respiration)

male:

Malaise (a feeling of general discomfort or uneasiness)

What are the common drug interactions of Minivelle and Enbrel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Ear infection
Infusion related reaction
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Sinusitis (inflammation of sinus)
Upper respiratory tract infection
Urinary tract infection
Arthropathy
Asthenia (weakness)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Cardiac disorder

50-59:

Pain
Abdominal pain upper
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Feeling hot
Headache (pain in head)
Hot flush (sudden feelings of heat)
Injection site haemorrhage (bleeding from injection site)
Palpitations (feelings or sensations that your heart is pounding or racing)
Tinnitus (a ringing in the ears)

60+:

Dyspnoea (difficult or laboured respiration)
Malaise (a feeling of general discomfort or uneasiness)
Bone pain
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Connective tissue disorder (any disease that has the connective tissues of the body)
Constipation
Cough
Drug intolerance (drug sensitivity)
Fibromyalgia (a long-term condition which causes pain all over the body)
Hot flush (sudden feelings of heat)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 7 people, 25.00%
Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 4 people, 14.29%
Primary Immunodeficiency Syndrome: 3 people, 10.71%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 7.14%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 7.14%
Asthma: 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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