Minivelle and Hydroxyzine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Minivelle (estradiol) and Hydroxyzine (hydroxyzine hydrochloride). Common drug interactions include migraine among females.

The phase IV clinical study analyzes what interactions people have when they take Minivelle and Hydroxyzine. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Minivelle?

Minivelle has active ingredients of estradiol. eHealthMe is studying from 3,480 Minivelle users. Check the latest studies of Minivelle.

What is Hydroxyzine?

Hydroxyzine has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 54,069 Hydroxyzine users. Check the latest studies of Hydroxyzine.



On Jul, 11, 2026

14 people who take Minivelle and Hydroxyzine together, and have interactions are studied.

Minivelle and Hydroxyzine drug interactions.

What are the common drug interactions of Minivelle and Hydroxyzine, by gender? *:

female:

  1. Migraine (headache)
  2. Hereditary angioedema (recurrent episodes of severe swelling)
  3. Dry skin
  4. Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain)
  5. Head discomfort
  6. Immunoglobulins increased
  7. Malaise (a feeling of general discomfort or uneasiness)
  8. Sneezing
  9. Tinnitus (a ringing in the ears)
  10. Vision blurred

male:

n/a

What are the common drug interactions of Minivelle and Hydroxyzine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Ankle fracture
  2. Fall
  3. Fibula fracture
  4. Headache (pain in head)
  5. Limb injury
  6. Migraine (headache)
  7. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  8. Nephrolithiasis (calculi in the kidneys)
  9. Pneumonia
  10. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

40-49:

  1. Abdominal discomfort
  2. Abdominal pain upper
  3. Headache (pain in head)
  4. Myalgia (muscle pain)
  5. Nausea (feeling of having an urge to vomit)

50-59:

  1. Dyspepsia (indigestion)
  2. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  3. Oesophageal pain
  4. Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)

60+:

  1. Bacterial infection

What are the existing conditions these people have? *

  1. Asthma: 7 people, 50.00%
  2. Immune System Disorder: 6 people, 42.86%
  3. Sleep Disorder: 2 people, 14.29%
  4. Urinary Tract Infection: 1 person, 7.14%
  5. Serum Ferritin Decreased: 1 person, 7.14%
  6. Seasonal Allergy (allergic condition due to certain season): 1 person, 7.14%
  7. Pain: 1 person, 7.14%
  8. Muscle Spasms (muscle contraction): 1 person, 7.14%
  9. Multiple Allergies (allergy to multiple agents): 1 person, 7.14%
  10. Iron Deficiency Anaemia: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Minivelle and Hydroxyzine?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Minivelle and Hydroxyzine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Minivelle:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Hydroxyzine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Minivelle and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydroxyzine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on estradiol and hydroxyzine hydrochloride (the active ingredients of Minivelle and Hydroxyzine, respectively), and Minivelle and Hydroxyzine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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