Minocin and Hydrochlorothiazide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Minocin (minocycline hydrochloride) and Hydrochlorothiazide (hydrochlorothiazide). Common drug interactions include chronic kidney disease among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Minocin and Hydrochlorothiazide. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Minocin?

Minocin has active ingredients of minocycline hydrochloride. It is often used in acne. eHealthMe is studying from 2,278 Minocin users. Check the latest studies of Minocin.

What is Hydrochlorothiazide?

Hydrochlorothiazide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 182,194 Hydrochlorothiazide users. Check the latest studies of Hydrochlorothiazide.

On Jul, 11, 2026

19 people who take Minocin and Hydrochlorothiazide together, and have interactions are studied.

Minocin and Hydrochlorothiazide drug interactions.

What are the common drug interactions of Minocin and Hydrochlorothiazide, by gender? *:

female:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)
Diarrhoea
Fall
Hypoaesthesia (reduced sense of touch or sensation)
Stomatitis (inflammation of mucous membrane of mouth)
Alopecia (absence of hair from areas of the body)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Asthenia (weakness)

male:

Anxiety
Depression
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
Fatigue (feeling of tiredness)
Irritability
Muscle cramps (painful sensations caused by muscle contraction)
Suicidal ideation
Tremor (trembling or shaking movements in one or more parts of your body)
Vision blurred

What are the common drug interactions of Minocin and Hydrochlorothiazide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Emotional distress
Injury
Pain
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))

40-49:

Depression
Fatigue (feeling of tiredness)
Suicidal ideation

50-59:

Blood potassium decreased
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
Muscle cramps (painful sensations caused by muscle contraction)
Pneumonia

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Chapped lips (cracking, fissuring, and peeling of the skin f lip)
Decreased appetite
Disease progression
Dizziness
Drug hypersensitivity
Electrolyte depletion (act of decreasing electrolyte markedly)
Fatigue (feeling of tiredness)
Gastrointestinal tract irritation

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 15.79%
Wheezing (a high-pitched whistling sound made while you breath): 1 person, 5.26%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 1 person, 5.26%
Dry Eyes (lack of adequate tears): 1 person, 5.26%
Headache (pain in head): 1 person, 5.26%
Infection: 1 person, 5.26%
Insomnia (sleeplessness): 1 person, 5.26%
Lung Neoplasm Malignant (cancer tumour of lung): 1 person, 5.26%
Neuralgia (pain in one or more nerves): 1 person, 5.26%
Urination - Excessive Volume: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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