Minoxidil and Actonel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Minoxidil (minoxidil) and Actonel (risedronate sodium). Common drug interactions include mitral valve disease among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Minoxidil and Actonel. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Minoxidil?

Minoxidil has active ingredients of minoxidil. It is often used in hair loss. eHealthMe is studying from 29,925 Minoxidil users. Check the latest studies of Minoxidil.

What is Actonel?

Actonel has active ingredients of risedronate sodium. It is often used in osteoporosis. eHealthMe is studying from 29,369 Actonel users. Check the latest studies of Actonel.

On Jul, 05, 2026

22 people who take Minoxidil and Actonel together, and have interactions are studied.

Minoxidil and Actonel drug interactions.

What are the common drug interactions of Minoxidil and Actonel, by gender? *:

female:

Mitral valve disease (disease of mitral valve of heart)
Mobility decreased (ability to move is reduced)
Multiple fractures
Muscle tightness
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Oedema peripheral (superficial swelling)
Osteoma (a new piece of bone usually growing on another piece of bone, typically the skull. it is a benign tumour)
Pigmentation disorder (disturbances of human skin colour)
Pruritus generalised (generalized itching)

male:

Arthralgia (joint pain)
Chronic kidney disease
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Hypotension (abnormally low blood pressure)
International normalised ratio increased
Leukocytosis (increased white blood cells)
Lung hyperinflation (inspiration of more than normal)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Myalgia (muscle pain)

What are the common drug interactions of Minoxidil and Actonel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal abscess (collection of pus in abdomen)
Abdominal pain
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Arthralgia (joint pain)
Back pain
Blood creatinine increased
Chills (felling of cold)
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Dyspnoea (difficult or laboured respiration)

50-59:

Chronic kidney disease
Glomerulonephritis (a group of conditions that affect parts of the kidneys called glomeruli)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Arthropathy
Deformity (disfigurement)
Drug hypersensitivity
Dry skin
Erythema multiforme (a type of hypersensitivity reaction)

60+:

Asthenia (weakness)
Chronic kidney disease
Fall
Femur fracture
Fracture displacement
Hair colour changes
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Hypertrichosis (hair growth on the body in an amount considered abnormal)
Low turnover osteopathy (slow removal of old bone and its replacement by new bone)
Muscular weakness (muscle weakness)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 27.27%
High Blood Pressure: 5 people, 22.73%
Fluid Retention (an abnormal accumulation of fluid in the blood): 4 people, 18.18%
High Blood Cholesterol: 4 people, 18.18%
Infection: 3 people, 13.64%
Renal Disorder (kidney disease): 3 people, 13.64%
Acidosis (build-up of carbon dioxide in the blood): 3 people, 13.64%
Pain: 3 people, 13.64%
Itching: 2 people, 9.09%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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