Mint and Cymbalta drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mint (peppermint) and Cymbalta (duloxetine hydrochloride). Common drug interactions include dry mouth among females and chills among males.

The phase IV clinical study analyzes what interactions people have when they take Mint and Cymbalta. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Mint?

Mint has active ingredients of peppermint. eHealthMe is studying from 1,344 Mint users. Check the latest studies of Mint.

What is Cymbalta?

Cymbalta has active ingredients of duloxetine hydrochloride. It is often used in depression. eHealthMe is studying from 154,973 Cymbalta users. Check the latest studies of Cymbalta.

On Jul, 20, 2026

18 people who take Mint and Cymbalta together, and have interactions are studied.

What are the common drug interactions of Mint and Cymbalta, by gender? *:

female:

Dry mouth
Euphoric mood (excessively happy but may become angry or irritable)
Herpes virus infection
Memory impairment
Periodic limb movement disorder
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Somnolence (a state of near-sleep, a strong desire for sleep)
Therapeutic response decreased (less preventive response)
Tooth disorder (tooth disease)
Tooth fracture

male:

Chills (felling of cold)
Nausea (feeling of having an urge to vomit)
Vomiting

What are the common drug interactions of Mint and Cymbalta, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Foot fracture
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hand fracture
Nausea (feeling of having an urge to vomit)
Osteopenia (a condition where bone mineral density is lower than normal)
Rib fracture

40-49:

Abdominal distension
Euphoric mood (excessively happy but may become angry or irritable)
Fatigue (feeling of tiredness)
Therapeutic response decreased (less preventive response)
Tooth disorder (tooth disease)
Weight fluctuation
Malaise (a feeling of general discomfort or uneasiness)
Temporomandibular joint syndrome (pain at the temporomandibular joint due to various causes of increased muscle tension and spasm. it is believed that syndrome is a physical manifestation of psychological stress)

50-59:

Nausea (feeling of having an urge to vomit)
Tooth fracture
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Dyspnoea (difficult or laboured respiration)
Gait disturbance
Gastric disorder (disease of stomach)
Gingival disorder (gum disease)
Headache (pain in head)
Heart rate increased
Influenza like illness

60+:

Diarrhoea
Fall
Limb injury
Loss of consciousness
Nausea (feeling of having an urge to vomit)
Pain in extremity

What are the existing conditions these people have? *

Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 44.44%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 44.44%
Muscle Spasms (muscle contraction): 3 people, 16.67%
Irritable Bowel Syndrome: 3 people, 16.67%
Neuralgia (pain in one or more nerves): 3 people, 16.67%
Drowsiness: 3 people, 16.67%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 11.11%
Primary Progressive Multiple Sclerosis (primary progressive inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 2 people, 11.11%
Itching: 2 people, 11.11%
Migraine (headache): 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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