Miralax and Ascorbate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Miralax (polyethylene glycol 3350) and Ascorbate (vitamin c (ascorbic acid)). Common drug interactions include sinusitis among females and amnesia among males.

The phase IV clinical study analyzes what interactions people have when they take Miralax and Ascorbate. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Miralax?

Miralax has active ingredients of polyethylene glycol 3350. It is often used in constipation. eHealthMe is studying from 81,754 Miralax users. Check the latest studies of Miralax.

What is Ascorbate?

Ascorbate has active ingredients of vitamin c (ascorbic acid). eHealthMe is studying from 1,446 Ascorbate users. Check the latest studies of Ascorbate.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 15, 2026

37 people who take Miralax and Ascorbate together, and have interactions are studied.

Miralax and Ascorbate drug interactions.

What are the common drug interactions of Miralax and Ascorbate, by gender? *:

female:

  1. Sinusitis (inflammation of sinus)
  2. Anaemia (lack of blood)
  3. Blood immunoglobulin g decreased
  4. Nausea (feeling of having an urge to vomit)
  5. Infusion site extravasation (flow of (blood or lymph) from infusion site)
  6. Abdominal pain
  7. Cellulitis (infection under the skin)
  8. Dehydration (dryness resulting from the removal of water)
  9. Diarrhoea
  10. Ear pain

male:

  1. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  2. Asthenia (weakness)
  3. Platelet count decreased
  4. Proctitis (inflammation of the rectum and anus)
  5. Renal disorder (kidney disease)
  6. Restless legs syndrome (a powerful urge to move your legs)
  7. Balance disorder
  8. Cellulitis (infection under the skin)
  9. Dehydration (dryness resulting from the removal of water)
  10. Faeces discoloured

What are the common drug interactions of Miralax and Ascorbate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Oesophageal candidiasis (fungal infection of oesophagus)
  2. Proctitis (inflammation of the rectum and anus)

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Bradycardia (abnormally slow heart action)
  2. Cellulitis (infection under the skin)
  3. Ear pain
  4. Eye infection
  5. Eye pain
  6. Eye pruritus (eye itching)
  7. Hepatic siderosis (deposit of an abnormal quantity of iron in the liver)
  8. Hypokalaemia (low potassium)
  9. Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
  10. Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)

60+:

  1. Anaemia (lack of blood)
  2. Nausea (feeling of having an urge to vomit)
  3. Thrombocytopenia (decrease of platelets in blood)
  4. Ulcer haemorrhage (bleeding ulcer)
  5. Urinary tract infection
  6. Abdominal pain upper
  7. Atelectasis (partial or complete collapse of the lung)
  8. Blood creatinine increased
  9. Blood potassium decreased
  10. Death

What are the existing conditions these people have? *

  1. Immunodeficiency Common Variable: 5 people, 13.51%
  2. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 4 people, 10.81%
  3. Pain: 3 people, 8.11%
  4. Multiple Myeloma (cancer of the plasma cells): 3 people, 8.11%
  5. Insomnia (sleeplessness): 3 people, 8.11%
  6. Nausea (feeling of having an urge to vomit): 2 people, 5.41%
  7. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 5.41%
  8. Pelvic Pain: 2 people, 5.41%
  9. Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 2 people, 5.41%
  10. Skin Infection: 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Miralax and Ascorbate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Miralax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ascorbate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Miralax and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ascorbate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on polyethylene glycol 3350 and vitamin c (ascorbic acid) (the active ingredients of Miralax and Ascorbate, respectively), and Miralax and Ascorbate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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