Miralax and Fetzima drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Miralax (polyethylene glycol 3350) and Fetzima (levomilnacipran hydrochloride). Common drug interactions include nausea among females and lymphocyte count decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Miralax and Fetzima. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Miralax?

Miralax has active ingredients of polyethylene glycol 3350. It is often used in constipation. eHealthMe is studying from 81,754 Miralax users. Check the latest studies of Miralax.

What is Fetzima?

Fetzima has active ingredients of levomilnacipran hydrochloride. It is often used in depression. eHealthMe is studying from 2,077 Fetzima users. Check the latest studies of Fetzima.



On Jul, 10, 2026

17 people who take Miralax and Fetzima together, and have interactions are studied.

Miralax and Fetzima drug interactions.

What are the common drug interactions of Miralax and Fetzima, by gender? *:

female:

  1. Nausea (feeling of having an urge to vomit)
  2. Rash
  3. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  4. Therapeutic response unexpected
  5. Cystitis (inflammation of the wall of the bladder)
  6. Abdominal pain upper
  7. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  8. Chapped lips (cracking, fissuring, and peeling of the skin f lip)
  9. Insomnia (sleeplessness)
  10. Suicidal ideation

male:

  1. Lymphocyte count decreased
  2. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  3. Muscular weakness (muscle weakness)
  4. White blood cell count increased

What are the common drug interactions of Miralax and Fetzima, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  2. Muscular weakness (muscle weakness)
  3. Suicidal ideation
  4. White blood cell count increased
  5. Lymphocyte count decreased

60+:

  1. Arthralgia (joint pain)
  2. Dyskinesia (abnormality or impairment of voluntary movement)
  3. Hip arthroplasty
  4. Nasopharyngitis (inflammation of the nasopharynx)
  5. Nausea (feeling of having an urge to vomit)
  6. Rash
  7. Therapeutic response unexpected
  8. Chapped lips (cracking, fissuring, and peeling of the skin f lip)
  9. Urinary tract infection

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 47.06%
  2. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 17.65%
  3. Multiple Myeloma (cancer of the plasma cells): 3 people, 17.65%
  4. Urinary Incontinence (inability to control the flow of urine and involuntary urination): 2 people, 11.76%
  5. Neurodermatitis (a skin disorder characterized by long lasting itching and scratching): 2 people, 11.76%
  6. Drowsiness: 2 people, 11.76%
  7. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 11.76%
  8. Swelling: 1 person, 5.88%
  9. Renal Cell Carcinoma (a kidney cancer): 1 person, 5.88%
  10. Pain: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Miralax and Fetzima?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Miralax and Fetzima:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Miralax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Fetzima:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Miralax and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Fetzima and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on polyethylene glycol 3350 and levomilnacipran hydrochloride (the active ingredients of Miralax and Fetzima, respectively), and Miralax and Fetzima (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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