Mirapex and Aredia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mirapex (pramipexole dihydrochloride) and Aredia (pamidronate disodium). Common drug interactions include osteonecrosis of jaw among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Mirapex and Aredia. It is created by eHealthMe based on reports of 69 people who take the same drugs from the FDA, and is updated regularly.

What is Mirapex?

Mirapex has active ingredients of pramipexole dihydrochloride. It is often used in restless leg syndrome. eHealthMe is studying from 20,622 Mirapex users. Check the latest studies of Mirapex.

What is Aredia?

Aredia has active ingredients of pamidronate disodium. It is often used in breast cancer. eHealthMe is studying from 15,365 Aredia users. Check the latest studies of Aredia.



On Aug, 07, 2026

69 people who take Mirapex and Aredia together, and have interactions are studied.

Mirapex and Aredia drug interactions.

What are the common drug interactions of Mirapex and Aredia, by gender? *:

female:

  1. Osteonecrosis of jaw (death of bone of jaw)
  2. Fatigue (feeling of tiredness)
  3. Decreased interest
  4. Myalgia (muscle pain)
  5. Back pain
  6. Dyspnoea (difficult or laboured respiration)
  7. Fall
  8. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  9. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  10. Arthralgia (joint pain)

male:

  1. Anxiety
  2. Decreased interest
  3. Bone disorder
  4. Pneumonia
  5. Bone pain
  6. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  7. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  8. Spinal compression fracture (fracture due to spinal compression on bone)
  9. Asthenia (weakness)
  10. Dyspnoea (difficult or laboured respiration)

What are the common drug interactions of Mirapex and Aredia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Pharyngeal haemorrhage (pharyngeal bleeding)
  2. Pharyngolaryngeal pain
  3. Pneumonia
  4. Abdominal pain upper
  5. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  6. Non-small cell lung cancer (type of epithelial lung cancer)
  7. Oesophageal pain
  8. Throat irritation

40-49:

  1. Anaemia (lack of blood)
  2. Anxiety
  3. Bone disorder
  4. Disability
  5. Dyslipidaemia (abnormal amount of lipids)
  6. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  7. General physical health deterioration (weak health status)
  8. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
  9. Injury
  10. Pain

50-59:

  1. Fall
  2. Fatigue (feeling of tiredness)
  3. Osteomyelitis (infection of bone)
  4. Anaemia (lack of blood)
  5. Gait disturbance
  6. Anxiety
  7. Decreased interest
  8. Impaired healing
  9. Syncope (loss of consciousness with an inability to maintain postural tone)
  10. Dyspnoea (difficult or laboured respiration)

60+:

  1. Anaemia (lack of blood)
  2. Anxiety
  3. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  4. Spinal osteoarthritis (joint cartilage loss in spine)
  5. Dizziness
  6. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  7. Spinal compression fracture (fracture due to spinal compression on bone)
  8. Bone disorder
  9. Asthenia (weakness)
  10. Chest pain

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 42 people, 60.87%
  2. Diabetes: 11 people, 15.94%
  3. Bone Lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries): 11 people, 15.94%
  4. Metastases To Bone (cancer spreads to bone): 7 people, 10.14%
  5. Osteoporosis (bones weak and more likely to break): 6 people, 8.70%
  6. Constipation: 6 people, 8.70%
  7. Pain: 5 people, 7.25%
  8. High Blood Pressure: 5 people, 7.25%
  9. Bone Pain: 5 people, 7.25%
  10. Arthritis (form of joint disorder that involves inflammation of one or more joints): 5 people, 7.25%

* Approximation only. Some reports may have incomplete information.

Do you take Mirapex and Aredia?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Mirapex and Aredia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Mirapex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Aredia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mirapex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Aredia and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on pramipexole dihydrochloride and pamidronate disodium (the active ingredients of Mirapex and Aredia, respectively), and Mirapex and Aredia (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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