Mirapex and Flecainide acetate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mirapex (pramipexole dihydrochloride) and Flecainide acetate (flecainide acetate). Common drug interactions include fatigue among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Mirapex and Flecainide acetate. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Mirapex?

Mirapex has active ingredients of pramipexole dihydrochloride. It is often used in restless leg syndrome. eHealthMe is studying from 20,622 Mirapex users. Check the latest studies of Mirapex.

What is Flecainide acetate?

Flecainide acetate has active ingredients of flecainide acetate. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 7,176 Flecainide acetate users. Check the latest studies of Flecainide acetate.



On Aug, 06, 2026

27 people who take Mirapex and Flecainide acetate together, and have interactions are studied.

Mirapex and Flecainide acetate drug interactions.

What are the common drug interactions of Mirapex and Flecainide Acetate, by gender? *:

female:

  1. Fatigue (feeling of tiredness)
  2. Back pain
  3. Pain
  4. Pain in extremity
  5. Alopecia (absence of hair from areas of the body)
  6. Arthralgia (joint pain)
  7. Burning sensation
  8. Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
  9. Diarrhoea
  10. Dizziness

male:

  1. Asthenia (weakness)
  2. Acute myocardial infarction (acute heart attack)
  3. Headache (pain in head)
  4. Mood swings (an extreme or rapid change in mood)
  5. Muscular weakness (muscle weakness)
  6. Nausea (feeling of having an urge to vomit)
  7. Night sweats (sweating in night)
  8. Pain
  9. Pain in extremity
  10. Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)

What are the common drug interactions of Mirapex and Flecainide Acetate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Abnormal faeces (abnormal stool)
  2. Acute myocardial infarction (acute heart attack)
  3. Fall
  4. Oedema peripheral (superficial swelling)
  5. Pain in extremity

50-59:

  1. Hot flush (sudden feelings of heat)
  2. Somnolence (a state of near-sleep, a strong desire for sleep)
  3. Anxiety
  4. Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
  5. Fatigue (feeling of tiredness)
  6. Vomiting

60+:

  1. Asthenia (weakness)
  2. Diarrhoea
  3. Pain
  4. Platelet count increased
  5. Synovial cyst (cyst of joint filled with synovial fluid)
  6. Urinary tract infection
  7. Vitreous floaters (spots before the eyes)
  8. Abdominal pain
  9. Ascites (accumulation of fluid in the abdominal cavity)
  10. Back pain

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 18.52%
  2. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 14.81%
  3. Osteoporosis (bones weak and more likely to break): 3 people, 11.11%
  4. Depression: 3 people, 11.11%
  5. Parkinson's Disease: 2 people, 7.41%
  6. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 7.41%
  7. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 7.41%
  8. Heart Palpitations (feelings or sensations that your heart is pounding or racing): 2 people, 7.41%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 7.41%
  10. Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Mirapex and Flecainide acetate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Mirapex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Flecainide acetate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mirapex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Flecainide acetate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on pramipexole dihydrochloride and flecainide acetate (the active ingredients of Mirapex and Flecainide acetate, respectively), and Mirapex and Flecainide acetate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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