Mirapex and Macrodantin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mirapex (pramipexole dihydrochloride) and Macrodantin (nitrofurantoin, macrocrystalline). Common drug interactions include hallucination among females and cellulitis among males.

The phase IV clinical study analyzes what interactions people have when they take Mirapex and Macrodantin. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Mirapex?

Mirapex has active ingredients of pramipexole dihydrochloride. It is often used in restless leg syndrome. eHealthMe is studying from 20,622 Mirapex users. Check the latest studies of Mirapex.

What is Macrodantin?

Macrodantin has active ingredients of nitrofurantoin, macrocrystalline. It is often used in urinary tract infection. eHealthMe is studying from 3,755 Macrodantin users. Check the latest studies of Macrodantin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

32 people who take Mirapex and Macrodantin together, and have interactions are studied.

Mirapex and Macrodantin drug interactions.

What are the common drug interactions of Mirapex and Macrodantin, by gender? *:

female:

Hallucination (an experience involving the perception of something not present)
Drug ineffective
Infusion related reaction
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Asthenia (weakness)
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Dizziness
Fall
Hallucination, visual (seeing things that aren't there)

male:

Cellulitis (infection under the skin)
Constipation
Dehydration (dryness resulting from the removal of water)
Hemiparesis (weakness on one side of the body)
Hypotension (abnormally low blood pressure)
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Productive cough
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)

What are the common drug interactions of Mirapex and Macrodantin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Swelling face
Urinary hesitation (difficulty in beginning the flow of urine)
Anxiety
Dizziness
Heart rate irregular
Palpitations (feelings or sensations that your heart is pounding or racing)
Pulmonary embolism (blockage of the main artery of the lung)
Abdominal pain upper
Asthenia (weakness)
Bedridden

50-59:

Infusion related reaction
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Sinusitis (inflammation of sinus)
Arrhythmia (irregular heartbeat)
Asthenia (weakness)
Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
Dehydration (dryness resulting from the removal of water)
Depressed level of consciousness
Fatigue (feeling of tiredness)

60+:

Hallucination (an experience involving the perception of something not present)
Nausea (feeling of having an urge to vomit)
Renal cyst (kidney cyst)
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)
Vomiting
Abdominal discomfort
Adverse drug reaction
Arthralgia (joint pain)
Asthma

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 9 people, 28.12%
Parkinson's Disease: 4 people, 12.50%
Nausea (feeling of having an urge to vomit): 4 people, 12.50%
Rosacea (a skin condition that causes facial redness): 3 people, 9.38%
Pain: 3 people, 9.38%
Infection: 3 people, 9.38%
Hypoglycemia (low blood sugar): 3 people, 9.38%
Hallucinations (sensations that appear real but are created by your mind): 3 people, 9.38%
Delusion (a false belief or opinion): 3 people, 9.38%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 3 people, 9.38%

* Approximation only. Some reports may have incomplete information.

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