Mirapex and Ocrevus drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mirapex (pramipexole dihydrochloride) and Ocrevus (ocrelizumab). Common drug interactions include pyrexia among females and multiple sclerosis among males.

The phase IV clinical study analyzes what interactions people have when they take Mirapex and Ocrevus. It is created by eHealthMe based on reports of 76 people who take the same drugs from the FDA, and is updated regularly.

What is Mirapex?

Mirapex has active ingredients of pramipexole dihydrochloride. It is often used in restless leg syndrome. eHealthMe is studying from 20,622 Mirapex users. Check the latest studies of Mirapex.

What is Ocrevus?

Ocrevus has active ingredients of ocrelizumab. eHealthMe is studying from 56,583 Ocrevus users. Check the latest studies of Ocrevus.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

76 people who take Mirapex and Ocrevus together, and have interactions are studied.

What are the common drug interactions of Mirapex and Ocrevus, by gender? *:

female:

Pyrexia (fever)
Red blood cell sedimentation rate increased
Secondary progressive multiple sclerosis (a stage of ms which comes after relapsing remitting ms in many cases)
Sepsis (a severe blood infection that can lead to organ failure and death)
Tooth fracture
Urticaria (rash of round, red welts on the skin that itch intensely)
Vitamin b12 increased
Vitamin d decreased
Abscess (pus)
Constipation

male:

Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Pyrexia (fever)
Pneumonia
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Obstructive sleep apnoea syndrome (frequent pauses in breathing during sleep usually accompanied by loud snoring)
Postoperative thoracic procedure complication
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Type 2 diabetes mellitus
Vitamin b12 deficiency
Vitamin d deficiency

What are the common drug interactions of Mirapex and Ocrevus, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anxiety
Asthenia (weakness)
Fall
Fatigue (feeling of tiredness)
Influenza like illness
Insomnia (sleeplessness)
Memory impairment
Neuralgia (pain in one or more nerves)
Oral herpes (viral infection of mouth)
Tooth fracture

40-49:

Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Balance disorder
Fatigue (feeling of tiredness)
Pain
Gait disturbance
Depression
Fall
Migraine (headache)
Mobility decreased (ability to move is reduced)
Muscle spasms (muscle contraction)

50-59:

Heart rate increased
Hot flush (sudden feelings of heat)
Hypercholesterolaemia (high levels of cholesterol in the blood)
Lymphoedema (localized fluid retention and tissue swelling)
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Muscular weakness (muscle weakness)
Nasopharyngitis (inflammation of the nasopharynx)
Nausea (feeling of having an urge to vomit)
Pain in extremity

60+:

Urinary tract infection
Diarrhoea
Dysphagia (a condition in which swallowing is difficult or painful)
Erythema (redness of the skin)
Fatigue (feeling of tiredness)
Headache (pain in head)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Memory impairment
Migraine (headache)

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 25 people, 32.89%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 24 people, 31.58%
Primary Progressive Multiple Sclerosis (primary progressive inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 12 people, 15.79%
Pain: 12 people, 15.79%
Secondary Progressive Multiple Sclerosis (a stage of ms which comes after relapsing remitting ms in many cases): 11 people, 14.47%
Gait Disturbance: 9 people, 11.84%
Muscle Spasms (muscle contraction): 8 people, 10.53%
Depression: 8 people, 10.53%
Stress And Anxiety: 7 people, 9.21%
Neuralgia (pain in one or more nerves): 7 people, 9.21%

* Approximation only. Some reports may have incomplete information.

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