Mirapex and Sennosides drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mirapex (pramipexole dihydrochloride) and Sennosides (senna). Common drug interactions include arthritis among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Mirapex and Sennosides. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Mirapex?

Mirapex has active ingredients of pramipexole dihydrochloride. It is often used in restless leg syndrome. eHealthMe is studying from 20,622 Mirapex users. Check the latest studies of Mirapex.

What is Sennosides?

Sennosides has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 8,247 Sennosides users. Check the latest studies of Sennosides.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

11 people who take Mirapex and Sennosides together, and have interactions are studied.

Mirapex and Sennosides drug interactions.

What are the common drug interactions of Mirapex and Sennosides, by gender? *:

female:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Cholecystitis acute (rapid infection of gallbladder)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Colitis (inflammation of colon)
Diarrhoea
Fatigue (feeling of tiredness)
Headache (pain in head)
Hypokalaemia (low potassium)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Hypotension (abnormally low blood pressure)

male:

Death
Dementia (madness)
Abnormal behaviour
Blood pressure decreased
Blood pressure inadequately controlled
Blood pressure systolic increased
Cellulitis (infection under the skin)
Cerebral atrophy (decrement in size of brain)
Depressed level of consciousness
Immune system disorder

What are the common drug interactions of Mirapex and Sennosides, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Colitis (inflammation of colon)
Diarrhoea
Hypokalaemia (low potassium)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Hypotension (abnormally low blood pressure)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Pain
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)

50-59:

Cholecystitis acute (rapid infection of gallbladder)
Death

60+:

Dementia (madness)
Dysphagia (a condition in which swallowing is difficult or painful)
Blood pressure decreased
Blood pressure inadequately controlled
Blood pressure systolic increased
Cellulitis (infection under the skin)
Cerebral atrophy (decrement in size of brain)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Death
Depressed level of consciousness

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 18.18%
Parkinson's Disease: 2 people, 18.18%
Depression: 2 people, 18.18%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 18.18%
High Blood Pressure: 2 people, 18.18%
Stress And Anxiety: 1 person, 9.09%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 9.09%
Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues): 1 person, 9.09%
Adverse Event: 1 person, 9.09%
Allergic Rhinitis: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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