Mircera and Medrol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mircera (methoxy polyethylene glycol-epoetin beta) and Medrol (methylprednisolone). Common drug interactions include aplasia pure red cell among females and cytomegalovirus test positive among males.

The phase IV clinical study analyzes what interactions people have when they take Mircera and Medrol. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Mircera?

Mircera has active ingredients of methoxy polyethylene glycol-epoetin beta. eHealthMe is studying from 10,321 Mircera users. Check the latest studies of Mircera.

What is Medrol?

Medrol has active ingredients of methylprednisolone. It is often used in rheumatoid arthritis. eHealthMe is studying from 24,443 Medrol users. Check the latest studies of Medrol.

On Aug, 06, 2026

33 people who take Mircera and Medrol together, and have interactions are studied.

What are the common drug interactions of Mircera and Medrol, by gender? *:

female:

Aplasia pure red cell (type of anaemia affecting the precursors to red blood cells but not to white blood cells)
Anaemia (lack of blood)
Dizziness
Drug hypersensitivity
Dyspnoea (difficult or laboured respiration)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Blood pressure increased
Duodenal ulcer
Feeling hot
Mallory-weiss syndrome (gastro-oesophageal laceration syndrome refers to bleeding from tears)

male:

Cytomegalovirus test positive
Neutropenia (an abnormally low number of neutrophils)
Osteomyelitis (infection of bone)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Cytomegalovirus enterocolitis (virus infection of intestine and colon)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Hydronephrosis (water inside the kidney)
Leukopenia (less number of white blood cells in blood)
Pyrexia (fever)
Aplasia pure red cell (type of anaemia affecting the precursors to red blood cells but not to white blood cells)

What are the common drug interactions of Mircera and Medrol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal distension
Blood creatinine increased
Chronic kidney disease
Pruritus (severe itching of the skin)
Rash

20-29:

Anaemia (lack of blood)
Malaise (a feeling of general discomfort or uneasiness)
Pallor
Back pain
Mobility decreased (ability to move is reduced)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Speech disorder

30-39:

Cytomegalovirus test positive
Febrile neutropenia (fever with reduced white blood cells)
Neutropenia (an abnormally low number of neutrophils)
Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
Apnoea (suspension of external breathing)
Cerebral infarction (less blood supply to brain resulting tissue damage)
Depressed level of consciousness
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
Osteomyelitis (infection of bone)
Pancreatitis acute (sudden inflammation of pancreas)

40-49:

Aplasia pure red cell (type of anaemia affecting the precursors to red blood cells but not to white blood cells)
Erythroblast count decreased
Infection
Osteomyelitis (infection of bone)
Haemoglobin decreased
Nephrogenic anaemia (anaemia due to kidney disease)
Pneumonia
Anaemia (lack of blood)
Pancreatitis acute (sudden inflammation of pancreas)

50-59:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Cytomegalovirus enterocolitis (virus infection of intestine and colon)
Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
Anaemia (lack of blood)
Arteriospasm coronary (spasm of the large- or medium-sized coronary arteries)
Dizziness
Folate deficiency (lack of folic acid)

60+:

Cytomegalovirus test positive
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Blood pressure increased
Duodenal ulcer
Feeling hot
Mallory-weiss syndrome (gastro-oesophageal laceration syndrome refers to bleeding from tears)
Pneumonia
Respiratory distress (difficulty in breathing)
Zinc deficiency
Adverse event

What are the existing conditions these people have? *

Nephrogenic Anaemia (anaemia due to kidney disease): 23 people, 69.70%
High Blood Pressure: 17 people, 51.52%
Anaemia (lack of blood): 13 people, 39.39%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 10 people, 30.30%
Immunodeficiency Disorders: 6 people, 18.18%
Gastritis (inflammation of stomach): 5 people, 15.15%
Vitamin D Decreased: 4 people, 12.12%
Electrolyte Imbalance: 4 people, 12.12%
Chronic Kidney Disease: 4 people, 12.12%
Cystinosis (abnormal accumulation of the amino acid cystine): 4 people, 12.12%

* Approximation only. Some reports may have incomplete information.

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