Mirena and Clindamycin hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mirena (levonorgestrel) and Clindamycin hydrochloride (clindamycin hydrochloride). Common drug interactions include pain among females and abdominal pain upper among males.

The phase IV clinical study analyzes what interactions people have when they take Mirena and Clindamycin hydrochloride. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Mirena?

Mirena has active ingredients of levonorgestrel. It is often used in birth control. eHealthMe is studying from 145,266 Mirena users. Check the latest studies of Mirena.

What is Clindamycin hydrochloride?

Clindamycin hydrochloride has active ingredients of clindamycin hydrochloride. It is often used in tooth abscess. eHealthMe is studying from 4,257 Clindamycin hydrochloride users. Check the latest studies of Clindamycin hydrochloride.



On Jul, 15, 2026

14 people who take Mirena and Clindamycin hydrochloride together, and have interactions are studied.

Mirena and Clindamycin hydrochloride drug interactions.

What are the common drug interactions of Mirena and Clindamycin Hydrochloride, by gender? *:

female:

  1. Pain
  2. Chronic kidney disease
  3. Emotional distress
  4. Injury
  5. Renal injury (kidney injury)
  6. Abdominal pain upper
  7. Blepharospasm (any abnormal contraction or twitch of the eyelid)
  8. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  9. Increased appetite
  10. Muscle disorder (muscle disease)

male:

  1. Abdominal pain upper
  2. Constipation
  3. Tooth disorder (tooth disease)
  4. Cough
  5. Heart rate decreased
  6. Hypersensitivity
  7. Insomnia (sleeplessness)
  8. Nausea (feeling of having an urge to vomit)
  9. Pain
  10. Rhinorrhoea (watery mucus discharge from the nose)

What are the common drug interactions of Mirena and Clindamycin Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Pain
  2. Emotional distress
  3. Injury
  4. Abdominal pain upper
  5. Blepharospasm (any abnormal contraction or twitch of the eyelid)
  6. Increased appetite
  7. Muscle disorder (muscle disease)
  8. Muscle spasms (muscle contraction)
  9. Parasomnia (sleep disorders that involve abnormal and unnatural movements, behaviours, emotions, perceptions)
  10. Rash

30-39:

  1. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  2. Ovarian neoplasm (tumour of ovary)
  3. Post procedural haematoma (post procedural clotting of blood)
  4. Pyrexia (fever)
  5. Appendicitis (inflammation of the appendix)

40-49:

  1. Chronic kidney disease
  2. Renal injury (kidney injury)
  3. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  4. Osteonecrosis (death of bone)
  5. Pain
  6. Skin lesion
  7. Urinary tract infection

50-59:

  1. Chronic kidney disease
  2. Renal injury (kidney injury)

60+:

n/a

What are the existing conditions these people have? *

  1. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 35.71%
  2. Drowsiness: 5 people, 35.71%
  3. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 35.71%
  4. Migraine (headache): 4 people, 28.57%
  5. Neuralgia (pain in one or more nerves): 2 people, 14.29%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 14.29%
  7. Abdominal Pain Upper: 2 people, 14.29%
  8. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 14.29%
  9. Rashes (redness): 2 people, 14.29%
  10. Pain: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Mirena and Clindamycin hydrochloride?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Mirena and Clindamycin hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Mirena:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Clindamycin hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mirena and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Clindamycin hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on levonorgestrel and clindamycin hydrochloride (the active ingredients of Mirena and Clindamycin hydrochloride, respectively), and Mirena and Clindamycin hydrochloride (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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