Mirena and Cyclophosphamide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mirena (levonorgestrel) and Cyclophosphamide (cyclophosphamide). Common drug interactions include facial paresis among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Mirena and Cyclophosphamide. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Mirena?

Mirena has active ingredients of levonorgestrel. It is often used in birth control. eHealthMe is studying from 145,266 Mirena users. Check the latest studies of Mirena.

What is Cyclophosphamide?

Cyclophosphamide has active ingredients of cyclophosphamide. It is often used in multiple myeloma. eHealthMe is studying from 185,240 Cyclophosphamide users. Check the latest studies of Cyclophosphamide.

On Jul, 25, 2026

31 people who take Mirena and Cyclophosphamide together, and have interactions are studied.

Mirena and Cyclophosphamide drug interactions.

What are the common drug interactions of Mirena and Cyclophosphamide, by gender? *:

female:

Facial paresis (weakness in facial muscle movement)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
Injury
Iucd complication
Malignant neoplasm progression (cancer tumour came back)
Meningitis tuberculous (a bacterial infection of the membranes covering the brain and spinal cord (meninges))
Monoparesis (one limb is very weak, but not completely paralyzed)
Muscle spasms (muscle contraction)
Pallor

male:

Anxiety
Depression
Uterine pain
Uterine perforation (accidental puncture of the uterus)
Vaginal haemorrhage (vaginal bleeding)
Pulmonary embolism (blockage of the main artery of the lung)
Abdominal pain
Chronic myeloid leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood)
Device dislocation
Drug ineffective

What are the common drug interactions of Mirena and Cyclophosphamide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Headache (pain in head)
Hot flush (sudden feelings of heat)
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Mucosal inflammation (infection of mucous membrane)
Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)
Neuropathy peripheral (surface nerve damage)
Neutropenia (an abnormally low number of neutrophils)
Oedema (fluid collection in tissue)
Pain

30-39:

Dysmenorrhoea (painful menstruation)
Cytolytic hepatitis (dissolution or destruction of a liver cell)
Liver disorder (liver diseases)
Cyst (a closed sac)
Pain
Rash
Synovial cyst (cyst of joint filled with synovial fluid)
Device expulsion
Ectopic pregnancy with intrauterine device
Genital haemorrhage (bleeding from genital)

40-49:

Alopecia (absence of hair from areas of the body)
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
C-reactive protein increased
Fatigue (feeling of tiredness)
Haemoglobin decreased
White blood cell count decreased
Anaemia (lack of blood)
Asthenia (weakness)
Breast neoplasm (non cancerous tumour of breast)
Diarrhoea infectious (bacteria, viruses, and other germs can cause diarrhoea)

50-59:

Infection
Pain
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Vomiting
Arthralgia (joint pain)
Blood immunoglobulin g increased
C-reactive protein increased
Complement factor c3 increased
Drug intolerance (drug sensitivity)

60+:

Anxiety
Depression
Uterine pain
Uterine perforation (accidental puncture of the uterus)
Vaginal haemorrhage (vaginal bleeding)
Pulmonary embolism (blockage of the main artery of the lung)
Emotional distress
Fear
Injury
Internal injury

What are the existing conditions these people have? *

Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 4 people, 12.90%
High Blood Pressure: 4 people, 12.90%
Breast Cancer: 4 people, 12.90%
Oedema (fluid collection in tissue): 3 people, 9.68%
Breast Cancer Female: 3 people, 9.68%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 6.45%
Dysmenorrhea (painful menstruation): 2 people, 6.45%
Allergic Rhinitis: 2 people, 6.45%
Anaemia (lack of blood): 2 people, 6.45%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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