Mirena and Echinacea drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mirena (levonorgestrel) and Echinacea (echinacea). Common drug interactions include anxiety among females.

The phase IV clinical study analyzes what interactions people have when they take Mirena and Echinacea. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Mirena?

Mirena has active ingredients of levonorgestrel. It is often used in birth control. eHealthMe is studying from 145,266 Mirena users. Check the latest studies of Mirena.

What is Echinacea?

Echinacea has active ingredients of echinacea. It is often used in immune response. eHealthMe is studying from 1,930 Echinacea users. Check the latest studies of Echinacea.

On Jul, 12, 2026

13 people who take Mirena and Echinacea together, and have interactions are studied.

What are the common drug interactions of Mirena and Echinacea, by gender? *:

female:

Anxiety
Dry throat
Sedation
Uterine perforation (accidental puncture of the uterus)
Chlamydial pelvic inflammatory disease (infection of pelvic organ by chlamydia bacteria)
Delirium (wild excitement)
Depression
Device expulsion
Drug ineffective
Feeling drunk

male:

n/a

What are the common drug interactions of Mirena and Echinacea, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Delirium (wild excitement)
Feeling drunk
Headache (pain in head)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nasopharyngitis (inflammation of the nasopharynx)
Pain
Pneumonia
Respiratory depression (respiration has a rate below 12 breaths)
Visual impairment

30-39:

Uterine perforation (accidental puncture of the uterus)
Anxiety
Depression
Injury
Medical device discomfort (difficulty due to medical devices)
Pain
Procedural pain
Scar

40-49:

Injection site pain

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 61.54%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 61.54%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.69%
Polyarthritis (arthritis which involves 5 or more joints simultaneously): 1 person, 7.69%
Migraine (headache): 1 person, 7.69%
Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 1 person, 7.69%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 7.69%
Heavy Or Prolong Menstrual Bleeding: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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