Mirena and Norethindrone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mirena (levonorgestrel) and Norethindrone (norethindrone). Common drug interactions include headache among females.

The phase IV clinical study analyzes what interactions people have when they take Mirena and Norethindrone. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Mirena?

Mirena has active ingredients of levonorgestrel. It is often used in birth control. eHealthMe is studying from 145,266 Mirena users. Check the latest studies of Mirena.

What is Norethindrone?

Norethindrone has active ingredients of norethindrone. It is often used in birth control. eHealthMe is studying from 1,610 Norethindrone users. Check the latest studies of Norethindrone.

On Aug, 11, 2026

15 people who take Mirena and Norethindrone together, and have interactions are studied.

Mirena and Norethindrone drug interactions.

What are the common drug interactions of Mirena and Norethindrone, by gender? *:

female:

Headache (pain in head)
Abdominal pain upper
Pyrexia (fever)
Staphylococcal infection (an infection with staphylococcus bacteria)
Swelling face
Urinary tract infection
Vomiting
Blood pressure decreased
Fall
Nasopharyngitis (inflammation of the nasopharynx)

male:

n/a

What are the common drug interactions of Mirena and Norethindrone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Contusion (a type of hematoma of tissue in which capillaries)

20-29:

Abdominal pain upper
Back pain
Fatigue (feeling of tiredness)
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Neck pain
Peripheral swelling
Procedural pain
Pyrexia (fever)

30-39:

Abdominal pain lower
Chest pain
Depression
Device dislocation
Dyspnoea (difficult or laboured respiration)
Genital haemorrhage (bleeding from genital)
Infection
Injury
Pain
Post procedural discomfort

40-49:

Arthralgia (joint pain)
Depression suicidal (suicide depressive disorder)
Syncope (loss of consciousness with an inability to maintain postural tone)
Wound
Myalgia (muscle pain)
Suicidal ideation
Abdominal pain
Device expulsion
Drug ineffective
Genital haemorrhage (bleeding from genital)

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Migraine Without Aura (headache without neurological problems): 4 people, 26.67%
Functional Gastrointestinal Disorder (functional problem in separate organs of gastrointestinal system): 4 people, 26.67%
Migraine (headache): 2 people, 13.33%
Menopause (end of monthly cycles in women): 2 people, 13.33%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 1 person, 6.67%
Seasonal Allergy (allergic condition due to certain season): 1 person, 6.67%
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung): 1 person, 6.67%
Pelvic Pain: 1 person, 6.67%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 6.67%
Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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