Misoprostol and Singulair drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Misoprostol (misoprostol) and Singulair (montelukast sodium). Common drug interactions include hypoaesthesia among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Misoprostol and Singulair. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Misoprostol?

Misoprostol has active ingredients of misoprostol. It is often used in abortion. eHealthMe is studying from 8,222 Misoprostol users. Check the latest studies of Misoprostol.

What is Singulair?

Singulair has active ingredients of montelukast sodium. It is often used in asthma. eHealthMe is studying from 129,752 Singulair users. Check the latest studies of Singulair.



On Jul, 13, 2026

57 people who take Misoprostol and Singulair together, and have interactions are studied.

Misoprostol and Singulair drug interactions.

What are the common drug interactions of Misoprostol and Singulair, by gender? *:

female:

  1. Hypoaesthesia (reduced sense of touch or sensation)
  2. Injection site pain
  3. Low density lipoprotein
  4. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  5. Ovarian cyst (fluid filled sac of the ovary)
  6. Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
  7. Somnolence (a state of near-sleep, a strong desire for sleep)
  8. Vaginal odour
  9. Vocal cord thickening
  10. Infusion related reaction

male:

  1. Chronic kidney disease
  2. Drug ineffective
  3. Balance disorder
  4. Blood glucose increased
  5. Blood pressure increased
  6. Constipation
  7. Decreased appetite
  8. Dry mouth
  9. Dyspnoea (difficult or laboured respiration)
  10. Fall

What are the common drug interactions of Misoprostol and Singulair, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Drug ineffective
  2. Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
  3. Low density lipoprotein
  4. Vaginal odour
  5. Vocal cord thickening
  6. Abdominal distension
  7. Ankle fracture
  8. Arthralgia (joint pain)
  9. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  10. Back pain

30-39:

  1. Alopecia (absence of hair from areas of the body)
  2. Diarrhoea
  3. Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  4. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  5. Nausea (feeling of having an urge to vomit)
  6. Pruritus (severe itching of the skin)

40-49:

  1. Dizziness
  2. Injection site pain
  3. Ovarian cyst (fluid filled sac of the ovary)
  4. Arthralgia (joint pain)
  5. Blood glucose increased
  6. Drug ineffective
  7. Dry mouth
  8. Headache (pain in head)
  9. Hypoaesthesia (reduced sense of touch or sensation)
  10. Injection site haemorrhage (bleeding from injection site)

50-59:

  1. Urinary tract disorder
  2. Uterine contractions
  3. Vomiting
  4. Weight decreased
  5. Chronic kidney disease
  6. Renal failure (kidney dysfunction)
  7. Memory impairment
  8. Depression
  9. Gastric ulcer (stomach ulcer)
  10. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

60+:

  1. Pain
  2. Fatigue (feeling of tiredness)
  3. Cough
  4. Dyspnoea (difficult or laboured respiration)
  5. Facial bones fracture (bone fracture of face)
  6. Gait disturbance
  7. Hypersomnia (excessive daytime sleepiness (eds))
  8. Injection site erythema (redness at injection site)
  9. Insomnia (sleeplessness)
  10. Neck pain

What are the existing conditions these people have? *

  1. Arthritis (form of joint disorder that involves inflammation of one or more joints): 11 people, 19.30%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 17.54%
  3. High Blood Pressure: 8 people, 14.04%
  4. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 12.28%
  5. Stress And Anxiety: 7 people, 12.28%
  6. Hypersensitivity: 7 people, 12.28%
  7. Pain: 6 people, 10.53%
  8. Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 6 people, 10.53%
  9. High Blood Cholesterol: 5 people, 8.77%
  10. Migraine (headache): 4 people, 7.02%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Misoprostol and Singulair:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Misoprostol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Singulair:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Misoprostol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Singulair and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on misoprostol and montelukast sodium (the active ingredients of Misoprostol and Singulair, respectively), and Misoprostol and Singulair (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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