Mitoxantrone and Desyrel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mitoxantrone (mitoxantrone hydrochloride) and Desyrel (trazodone hydrochloride). Common drug interactions include deep vein thrombosis among males.

The phase IV clinical study analyzes what interactions people have when they take Mitoxantrone and Desyrel. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Mitoxantrone?

Mitoxantrone has active ingredients of mitoxantrone hydrochloride. eHealthMe is studying from 8,125 Mitoxantrone users. Check the latest studies of Mitoxantrone.

What is Desyrel?

Desyrel has active ingredients of trazodone hydrochloride. It is often used in insomnia. eHealthMe is studying from 6,595 Desyrel users. Check the latest studies of Desyrel.

On Jul, 27, 2026

12 people who take Mitoxantrone and Desyrel together, and have interactions are studied.

Mitoxantrone and Desyrel drug interactions.

What are the common drug interactions of Mitoxantrone and Desyrel, by gender? *:

female:

n/a

male:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Oesophagitis (inflammation of oesophagus)
Activities of daily living impaired
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Ascites (accumulation of fluid in the abdominal cavity)
Atelectasis (partial or complete collapse of the lung)
Bone disorder
Constipation
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)

What are the common drug interactions of Mitoxantrone and Desyrel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Ascites (accumulation of fluid in the abdominal cavity)
Atelectasis (partial or complete collapse of the lung)
Bone disorder
Colonic polyp (extra part of colon tissue grow in intestine)
Constipation
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Decreased appetite
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dehydration (dryness resulting from the removal of water)
Diarrhoea

60+:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Chest pain
Blood creatinine increased
Blood urea increased
Hypokalaemia (low potassium)
Platelet count decreased
Sinus arrhythmia (a naturally occurring variation in heart rate that occurs during a breathing cycle)
Spinal osteoarthritis (joint cartilage loss in spine)
Aortic valve sclerosis (narrowing of the aortic valve)
Blood urine present

What are the existing conditions these people have? *

Prostate Cancer Metastatic: 6 people, 50.00%
Bone Density Decreased: 5 people, 41.67%
Metastases To Bone (cancer spreads to bone): 1 person, 8.33%
Colon Cancer: 1 person, 8.33%
Bone Loss: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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