Mitoxantrone and Prilosec drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mitoxantrone (mitoxantrone hydrochloride) and Prilosec (omeprazole). Common drug interactions include dysphonia among females and bone disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Mitoxantrone and Prilosec. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Mitoxantrone?

Mitoxantrone has active ingredients of mitoxantrone hydrochloride. eHealthMe is studying from 8,125 Mitoxantrone users. Check the latest studies of Mitoxantrone.

What is Prilosec?

Prilosec has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 175,285 Prilosec users. Check the latest studies of Prilosec.

On Jul, 19, 2026

30 people who take Mitoxantrone and Prilosec together, and have interactions are studied.

Mitoxantrone and Prilosec drug interactions.

What are the common drug interactions of Mitoxantrone and Prilosec, by gender? *:

female:

Dysphonia (speech disorder attributable to a disorder of phonation)
Hyperkeratosis (thickening of the outer layer of the skin)
Lymphadenopathy mediastinal (an enlargement of the lymph nodes in the part of the chest that separates the lungs)
Reflux laryngitis (voice disorder caused by backflow of stomach fluids to the throat and voice box area)
Alopecia (absence of hair from areas of the body)
Fatigue (feeling of tiredness)
Haematochezia (passage of stools containing blood)
Mucosal ulceration (ulcers of mucous membrane)
Muscle twitching
Oral submucosal fibrosis

male:

Bone disorder
Osteonecrosis (death of bone)
Pneumonia
Syncope (loss of consciousness with an inability to maintain postural tone)
Coma (state of unconsciousness lasting more than six hours)
Confusion
Demyelination (loss of the myelin covering of some nerve fibres resulting in their impaired function)
Depressed level of consciousness
Encephalopathy (functioning of the brain is affected by some agent or condition)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

What are the common drug interactions of Mitoxantrone and Prilosec, by age (0-1 to 60+)? *:

0-1:

Oesophageal squamous cell carcinoma (cancer that begins in flat cells lining the oesophagus)
Abdominal distension
Acute respiratory distress syndrome
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Dyspnoea (difficult or laboured respiration)
Febrile neutropenia (fever with reduced white blood cells)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hyperbilirubinaemia (excess of bilirubin in the blood)
Ileus (a painful obstruction of the ileum or other part of the intestine)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Alopecia (absence of hair from areas of the body)
Anxiety
Hair colour changes
Hair disorder
Bone disorder
Osteonecrosis (death of bone)
Pain
Psychological trauma
Swelling
Tooth abscess (pus formation in tooth)

60+:

Bone disorder
Pain
Confusional state
Cyst (a closed sac)
Death
Dehydration (dryness resulting from the removal of water)
Dental caries
Depression
Diarrhoea
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 12 people, 40.00%
Breast Cancer: 10 people, 33.33%
Parkinson's Disease: 9 people, 30.00%
Osteoporosis (bones weak and more likely to break): 9 people, 30.00%
Osteopenia (a condition where bone mineral density is lower than normal): 9 people, 30.00%
Breast Cancer Female: 4 people, 13.33%
Prostate Cancer: 3 people, 10.00%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 10.00%
Prostate Cancer Metastatic: 2 people, 6.67%
Pain: 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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