Mobic and Premphase drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mobic (meloxicam) and Premphase (estrogens, conjugated; medroxyprogesterone acetate). Common drug interactions include anaemia of chronic disease among females.

The phase IV clinical study analyzes what interactions people have when they take Mobic and Premphase. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Mobic?

Mobic has active ingredients of meloxicam. It is often used in arthritis. eHealthMe is studying from 26,684 Mobic users. Check the latest studies of Mobic.

What is Premphase?

Premphase has active ingredients of estrogens, conjugated; medroxyprogesterone acetate. eHealthMe is studying from 2,262 Premphase users. Check the latest studies of Premphase.



On Jul, 15, 2026

15 people who take Mobic and Premphase together, and have interactions are studied.

Mobic and Premphase drug interactions.

What are the common drug interactions of Mobic and Premphase, by gender? *:

female:

  1. Anaemia of chronic disease
  2. Anaphylactic reaction (serious allergic reaction)
  3. Diarrhoea
  4. Dyspnoea exertional (breathlessness or shortness of breath)
  5. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  6. Histoplasmosis (infection caused by breathing in spores of a fungus)
  7. Hypertension (high blood pressure)
  8. Infection
  9. Interstitial lung disease
  10. Jaw disorder (jaw disease)

male:

n/a

What are the common drug interactions of Mobic and Premphase, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
  2. Anaemia of chronic disease
  3. Anaphylactic reaction (serious allergic reaction)
  4. Angina pectoris (chest pain due to ischemia of the heart muscle)
  5. Angioedema (rapid swelling of the dermis)
  6. Anxiety
  7. Arrhythmia (irregular heartbeat)
  8. Arteritis (inflammation of the walls of arteries)
  9. Arthropathy
  10. Asthma

30-39:

n/a

40-49:

  1. Fibromyalgia (a long-term condition which causes pain all over the body)
  2. Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin)
  3. Headache (pain in head)
  4. Insomnia (sleeplessness)
  5. Nervousness
  6. Pruritus generalised (generalized itching)
  7. Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)

50-59:

n/a

60+:

  1. Abdominal pain
  2. Anaemia of chronic disease
  3. Cardiac failure chronic
  4. Contusion (a type of hematoma of tissue in which capillaries)
  5. Decreased appetite
  6. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  7. Dental caries
  8. Dental discomfort
  9. Diarrhoea
  10. Diverticulum intestinal haemorrhagic (a pouch that is attached to the first part of the small intestine with bleeding)

What are the existing conditions these people have? *

  1. Stress And Anxiety: 13 people, 86.67%
  2. Pain In Jaw: 13 people, 86.67%
  3. Multiple Myeloma (cancer of the plasma cells): 13 people, 86.67%
  4. Rhinitis Seasonal (a medical term for irritation and inflammation of the mucous membrane inside the nose seasonal): 1 person, 6.67%
  5. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 6.67%
  6. Pain: 1 person, 6.67%
  7. Osteopenia (a condition where bone mineral density is lower than normal): 1 person, 6.67%
  8. Nausea (feeling of having an urge to vomit): 1 person, 6.67%
  9. Migraine (headache): 1 person, 6.67%
  10. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Mobic and Premphase?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Mobic and Premphase:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Mobic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Premphase:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mobic and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Premphase and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on meloxicam and estrogens, conjugated; medroxyprogesterone acetate (the active ingredients of Mobic and Premphase, respectively), and Mobic and Premphase (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: