Modafinil and Welchol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Modafinil (modafinil) and Welchol (colesevelam hydrochloride). Common drug interactions include malaise among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Modafinil and Welchol. It is created by eHealthMe based on reports of 91 people who take the same drugs from the FDA, and is updated regularly.

What is Modafinil?

Modafinil has active ingredients of modafinil. It is often used in narcolepsy. eHealthMe is studying from 20,805 Modafinil users. Check the latest studies of Modafinil.

What is Welchol?

Welchol has active ingredients of colesevelam hydrochloride. It is often used in high blood cholesterol. eHealthMe is studying from 11,309 Welchol users. Check the latest studies of Welchol.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

91 people who take Modafinil and Welchol together, and have interactions are studied.

Modafinil and Welchol drug interactions.

What are the common drug interactions of Modafinil and Welchol, by gender? *:

female:

Malaise (a feeling of general discomfort or uneasiness)
Migraine (headache)
Swelling
Abdominal discomfort
Carpal tunnel decompression
Chronic kidney disease
Ear discomfort
Fractured coccyx (fracture tail bone)
Headache (pain in head)
Hemiplegia (paralysis of one side of the body)

male:

Drug ineffective
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Fibromyalgia (a long-term condition which causes pain all over the body)
Finger deformity (a deformed position of the finger)
Foot deformity (functional disability of foot)
Headache (pain in head)
Hepatic enzyme increased
Hypokinesia (decreased bodily movement)
Limb discomfort (discomfort in leg)

What are the common drug interactions of Modafinil and Welchol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Cough
Headache (pain in head)

40-49:

Drug ineffective
Thyroidectomy
Dizziness
Dysphagia (a condition in which swallowing is difficult or painful)
Ear discomfort
Fall
Fractured coccyx (fracture tail bone)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate)
Muscle tightness

50-59:

Drug hypersensitivity
Stress cardiomyopathy (stress-induced chronic disease of the heart muscle)
Blood pressure increased
Arthralgia (joint pain)
Ear disorder
Foot fracture
Abscess rupture (pus release from the point of abscess)
Arthropathy
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Crying

60+:

Abdominal discomfort
Bladder hypertrophy (bladder overgrowth- increase in cell size)
Pneumonia
Renal cyst (kidney cyst)
Tibia fracture (fracture of lower leg bone)
Blood testosterone decreased
Cystitis (inflammation of the wall of the bladder)
Dry eye (lack of adequate tears)
Eye disorder
Fall

What are the existing conditions these people have? *

Cataplexy (loss of muscle tone accompanied by full conscious awareness): 23 people, 25.27%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 6.59%
Seasonal Affective Disorder (a type of depression that occurs at a certain time of the year, usually in the winter): 5 people, 5.49%

* Approximation only. Some reports may have incomplete information.

Do you take Modafinil and Welchol?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously