Moduretic 5-50 and Haldol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Moduretic 5-50 (amiloride hydrochloride; hydrochlorothiazide) and Haldol (haloperidol). Common drug interactions include blood creatine phosphokinase increased among females and hypotension among males.

The phase IV clinical study analyzes what interactions people have when they take Moduretic 5-50 and Haldol. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Moduretic 5-50?

Moduretic 5-50 has active ingredients of amiloride hydrochloride; hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 3,224 Moduretic 5-50 users. Check the latest studies of Moduretic 5-50.

What is Haldol?

Haldol has active ingredients of haloperidol. It is often used in schizophrenia. eHealthMe is studying from 23,102 Haldol users. Check the latest studies of Haldol.



On Jul, 12, 2026

13 people who take Moduretic 5-50 and Haldol together, and have interactions are studied.

Moduretic 5-50 and Haldol drug interactions.

What are the common drug interactions of Moduretic 5-50 and Haldol, by gender? *:

female:

  1. Blood creatine phosphokinase increased
  2. Dyspnoea (difficult or laboured respiration)
  3. Malaise (a feeling of general discomfort or uneasiness)
  4. Tremor (trembling or shaking movements in one or more parts of your body)
  5. Agitation (state of anxiety or nervous excitement)
  6. Blood sodium decreased
  7. Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
  8. Cardiac arrest
  9. Chest pain
  10. Dehydration (dryness resulting from the removal of water)

male:

  1. Hypotension (abnormally low blood pressure)
  2. Sluggishness (lacking alertness)
  3. Infarction (obstruction of the blood supply to an organ or region of tissue)
  4. Lung infection
  5. Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
  6. Oedema peripheral (superficial swelling)
  7. Respiratory failure (inadequate gas exchange by the respiratory system)
  8. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  9. Self injurious behaviour
  10. Varicose vein (veins that have become enlarged and tortuous)

What are the common drug interactions of Moduretic 5-50 and Haldol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Hypotension (abnormally low blood pressure)
  2. Sluggishness (lacking alertness)
  3. Vomiting
  4. Drug abuse
  5. Self injurious behaviour

30-39:

n/a

40-49:

n/a

50-59:

  1. Agitation (state of anxiety or nervous excitement)
  2. Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
  3. Dehydration (dryness resulting from the removal of water)
  4. Depressed level of consciousness
  5. Miosis (constriction of the pupil of the eye, resulting from a normal response to an increase in light)
  6. Mucosal inflammation (infection of mucous membrane)
  7. Nephrogenic diabetes insipidus (a disorder in which a defect in the small tubes (tubules) in the kidneys causes a person to pass a large amount of urine)
  8. Oedema peripheral (superficial swelling)
  9. Pitting oedema (skin discoloration)
  10. Pneumonia

60+:

  1. Blood creatine phosphokinase increased
  2. Dyspnoea (difficult or laboured respiration)
  3. Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
  4. Dysphagia (a condition in which swallowing is difficult or painful)
  5. Enterobacter infection (infection caused by bacteria of the family enterobacteriaceae)
  6. Infarction (obstruction of the blood supply to an organ or region of tissue)
  7. Lung infection
  8. Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
  9. Oedema peripheral (superficial swelling)
  10. Pleurothotonus (neurological disorder which occurs due to prolonged exposure to antipsychotic drugs)

What are the existing conditions these people have? *

  1. Lung Cancer - Non-Small Cell (lung cancer): 3 people, 23.08%
  2. Parkinson's Disease: 1 person, 7.69%
  3. Depression: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Moduretic 5-50 and Haldol?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Moduretic 5-50 and Haldol:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Moduretic 5-50:

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Browse all side effects of Haldol:

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Browse all interactions between Moduretic 5-50 and drugs from A to Z:

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Browse all interactions between Haldol and drugs from A to Z:

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Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on amiloride hydrochloride; hydrochlorothiazide and haloperidol (the active ingredients of Moduretic 5-50 and Haldol, respectively), and Moduretic 5-50 and Haldol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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