Monopril and Cogentin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Monopril (fosinopril sodium) and Cogentin (benztropine mesylate). Common drug interactions include osteonecrosis among females and bipolar disorder among males.
The phase IV clinical study analyzes what interactions people have when they take Monopril and Cogentin. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.
What is Monopril?
Monopril has active ingredients of fosinopril sodium. It is often used in high blood pressure. eHealthMe is studying from 5,910 Monopril users. Check the latest studies of Monopril.
What is Cogentin?
Cogentin has active ingredients of benztropine mesylate. It is often used in tardive dyskinesia. eHealthMe is studying from 7,692 Cogentin users. Check the latest studies of Cogentin.
25 people who take Monopril and Cogentin together, and have interactions are studied.

What are the common drug interactions of Monopril and Cogentin, by gender? *:
female:
- Osteonecrosis (death of bone)
- Pain in jaw
- Pathological fracture (broken bone caused by disease)
- Post procedural infection
- Swelling face
- Ataxia (loss of full control of bodily movements)
- Bone disorder
- Cellulitis (infection under the skin)
- Cellulitis staphylococcal (a type of bacteria originated skin soft tissue infection)
- Confusion
male:
- Bipolar disorder (mood disorder)
- Cellulitis (infection under the skin)
- Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
- Upper respiratory tract infection
- Abdominal pain upper
- Activated partial thromboplastin time prolonged
- Anxiety
- Balance disorder
- Bradycardia (abnormally slow heart action)
- Breast pain
What are the common drug interactions of Monopril and Cogentin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Cellulitis (infection under the skin)
- Infection
- Abdominal pain
- Abscess jaw (tooth abscess or root abscess)
- Arthralgia (joint pain)
- Asthma
- Autoimmune hepatitis
- Bipolar disorder (mood disorder)
- Blood cholesterol increased
- Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
50-59:
- Balance disorder
- Confusional state
- Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
- Dizziness
- Dysarthria (speech disorder)
- Dyskinesia (abnormality or impairment of voluntary movement)
- Emotional disorder
- Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
60+:
- Cardiac failure congestive
- Abdominal pain upper
- Chest pain
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Coronary artery restenosis (recurrence of narrowing of artery)
- Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
- Drug dependence
- Dyspnoea (difficult or laboured respiration)
- Emotional distress
- Haemorrhoids (a swollen vein or group of veins in the region of the anus)
What are the existing conditions these people have? *
- Schizoaffective Disorder (a mental disorder characterized by disordered thought): 2 people, 8.00%
- Osteoporosis (bones weak and more likely to break): 2 people, 8.00%
- Depression: 2 people, 8.00%
- Bipolar Disorder (mood disorder): 2 people, 8.00%
* Approximation only. Some reports may have incomplete information.
Do you take Monopril and Cogentin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Monopril and Cogentin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Monopril:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Cogentin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Monopril and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cogentin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on fosinopril sodium and benztropine mesylate (the active ingredients of Monopril and Cogentin, respectively), and Monopril and Cogentin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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