Monopril and Cytoxan drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Monopril (fosinopril sodium) and Cytoxan (cyclophosphamide). Common drug interactions include anxiety among females and oedema peripheral among males.
The phase IV clinical study analyzes what interactions people have when they take Monopril and Cytoxan. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.
What is Monopril?
Monopril has active ingredients of fosinopril sodium. It is often used in high blood pressure. eHealthMe is studying from 5,910 Monopril users. Check the latest studies of Monopril.
What is Cytoxan?
Cytoxan has active ingredients of cyclophosphamide. It is often used in breast cancer. eHealthMe is studying from 19,693 Cytoxan users. Check the latest studies of Cytoxan.
44 people who take Monopril and Cytoxan together, and have interactions are studied.

What are the common drug interactions of Monopril and Cytoxan, by gender? *:
female:
- Anxiety
- Headache (pain in head)
- Nausea (feeling of having an urge to vomit)
- General physical health deterioration (weak health status)
- Mucosal inflammation (infection of mucous membrane)
- Vomiting
- Sinusitis (inflammation of sinus)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Osteonecrosis of jaw (death of bone of jaw)
- Depression
male:
- Oedema peripheral (superficial swelling)
- Pain
- Stasis dermatitis (skin inflammation caused by blood pooling in the veins in your legs)
- Mobility decreased (ability to move is reduced)
- Muscular weakness (muscle weakness)
- Osteonecrosis (death of bone)
- Tooth extraction
- Toothache (tooth pain)
- Acidosis (build-up of carbon dioxide in the blood)
- Acute myocardial infarction (acute heart attack)
What are the common drug interactions of Monopril and Cytoxan, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Pain
- Abortion (termination of pregnancy)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Bronchitis acute (acute inflammation of the mucous membrane in the bronchial tubes)
- Chest pain
- Chest tightness
- Complications of maternal exposure to therapeutic drugs
- Depression
- Drug dependence
40-49:
- Anxiety
- General physical health deterioration (weak health status)
- Headache (pain in head)
- Mucosal inflammation (infection of mucous membrane)
- Nausea (feeling of having an urge to vomit)
- Pain
- Vomiting
- Sinusitis (inflammation of sinus)
- Osteonecrosis of jaw (death of bone of jaw)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
50-59:
- Anxiety
- Pain
- Emotional distress
- Psychological trauma
- Abdominal pain
- Fatigue (feeling of tiredness)
- Haematocrit decreased
- Haemoglobin decreased
- Oral infection
- Alveolar osteitis (complication of wound healing following extraction of a tooth)
60+:
- Oedema peripheral (superficial swelling)
- Pain
- Osteonecrosis (death of bone)
- Stasis dermatitis (skin inflammation caused by blood pooling in the veins in your legs)
- Tooth extraction
- Toothache (tooth pain)
- Acidosis (build-up of carbon dioxide in the blood)
- Acute myocardial infarction (acute heart attack)
- Acute respiratory failure
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
What are the existing conditions these people have? *
- Pain: 7 people, 15.91%
- Nuclear Magnetic Resonance Imaging Brain: 6 people, 13.64%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 6 people, 13.64%
- Breast Cancer Female: 3 people, 6.82%
* Approximation only. Some reports may have incomplete information.
Do you take Monopril and Cytoxan?
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- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Monopril and Cytoxan:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Monopril:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Cytoxan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Monopril and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cytoxan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Hu P, Lu L, Hu B, Deng F, Fei WJ, "Cyclophosphamide‐Induced Hypertensive Encephalopathy in a Young Girl With Lupus", The Journal of Clinical Hypertension, 2012 Apr .
- Hu P, Lu L, Hu B, Deng F, Fei WJ, "Cyclophosphamide‐Induced Hypertensive Encephalopathy in a Young Girl With Lupus", The Journal of Clinical Hypertension, 2012 Apr .
How the study uses the data?
The study uses data from the FDA. It is based on fosinopril sodium and cyclophosphamide (the active ingredients of Monopril and Cytoxan, respectively), and Monopril and Cytoxan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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