Monopril and Pradaxa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Monopril (fosinopril sodium) and Pradaxa (dabigatran etexilate mesylate). Common drug interactions include gastrointestinal haemorrhage among females and upper gastrointestinal haemorrhage among males.

The phase IV clinical study analyzes what interactions people have when they take Monopril and Pradaxa. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Monopril?

Monopril has active ingredients of fosinopril sodium. It is often used in high blood pressure. eHealthMe is studying from 5,910 Monopril users. Check the latest studies of Monopril.

What is Pradaxa?

Pradaxa has active ingredients of dabigatran etexilate mesylate. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 86,906 Pradaxa users. Check the latest studies of Pradaxa.



On Aug, 10, 2026

30 people who take Monopril and Pradaxa together, and have interactions are studied.

Monopril and Pradaxa drug interactions.

What are the common drug interactions of Monopril and Pradaxa, by gender? *:

female:

  1. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  2. Abdominal discomfort
  3. Arthralgia (joint pain)
  4. Dizziness
  5. Dyspepsia (indigestion)
  6. Eye haemorrhage (bleeding in the eye)
  7. Fatigue (feeling of tiredness)
  8. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  9. Hyperchlorhydria (gastric acid levels are higher in stomach)
  10. International normalised ratio increased

male:

  1. Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
  2. Nausea (feeling of having an urge to vomit)
  3. Blood glucose increased
  4. Glycosylated haemoglobin increased
  5. Subileus
  6. Anaemia (lack of blood)
  7. Fall
  8. Hypercholesterolaemia (high levels of cholesterol in the blood)
  9. Oesophageal pain
  10. Pulmonary haemorrhage (acute bleeding from the lung)

What are the common drug interactions of Monopril and Pradaxa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Appendicitis (inflammation of the appendix)
  2. Subileus
  3. Blood glucose increased
  4. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  5. Eye haemorrhage (bleeding in the eye)
  6. Glycosylated haemoglobin increased
  7. Ocular hyperaemia (an abnormally large amount of blood in eye)

60+:

  1. Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
  2. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  3. Fatigue (feeling of tiredness)
  4. International normalised ratio increased
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Acute respiratory failure
  7. Asthenia (weakness)
  8. Diffuse large b-cell lymphoma stage iii (cancer of b cells, a type of white blood cell-stage iii)
  9. Fall
  10. Hypercholesterolaemia (high levels of cholesterol in the blood)

What are the existing conditions these people have? *

  1. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 7 people, 23.33%
  2. Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 13.33%
  3. Prostate Cancer: 3 people, 10.00%
  4. Fluid Retention (an abnormal accumulation of fluid in the blood): 3 people, 10.00%
  5. Polyarthritis (arthritis which involves 5 or more joints simultaneously): 2 people, 6.67%
  6. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 2 people, 6.67%
  7. Joint Pain: 2 people, 6.67%
  8. High Blood Cholesterol: 2 people, 6.67%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Monopril and Pradaxa?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Monopril and Pradaxa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Monopril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Pradaxa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Monopril and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pradaxa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on fosinopril sodium and dabigatran etexilate mesylate (the active ingredients of Monopril and Pradaxa, respectively), and Monopril and Pradaxa (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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