Monopril and Zelnorm drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Monopril (fosinopril sodium) and Zelnorm (tegaserod maleate). Common drug interactions include cardiomyopathy among females and diabetes mellitus among males.

The phase IV clinical study analyzes what interactions people have when they take Monopril and Zelnorm. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Monopril?

Monopril has active ingredients of fosinopril sodium. It is often used in high blood pressure. eHealthMe is studying from 5,910 Monopril users. Check the latest studies of Monopril.

What is Zelnorm?

Zelnorm has active ingredients of tegaserod maleate. eHealthMe is studying from 7,261 Zelnorm users. Check the latest studies of Zelnorm.

On Jul, 22, 2026

22 people who take Monopril and Zelnorm together, and have interactions are studied.

What are the common drug interactions of Monopril and Zelnorm, by gender? *:

female:

Cardiomyopathy (weakening of the heart muscle)
Cerebrovascular disorder (disease of brain)
Chest wall pain
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Costovertebral angle tenderness
Cystocele (a condition that occurs when the tough fibrous wall between a woman's bladder and her vagina is torn by childbirth)
Death
Dyspepsia (indigestion)
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
Emotional distress

male:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetes mellitus inadequate control
Acute myocardial infarction (acute heart attack)
Blood cholesterol increased
Blood triglycerides increased
Cardiac failure congestive
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Hyperglycaemia (high blood sugar)
Irritable bowel syndrome
Pancreatitis acute (sudden inflammation of pancreas)

What are the common drug interactions of Monopril and Zelnorm, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic gastroparesis (paralysis of the muscles of the stomach caused by diabetes)
Diabetic nephropathy (diabetic kidney disease)
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Ketoacidosis (high concentrations of ketone bodies in blood)
Pancreatitis (inflammation of pancreas)
Vision blurred
Diabetes mellitus inadequate control
Pancreatitis acute (sudden inflammation of pancreas)

40-49:

Pyrexia (fever)
Respiratory failure (inadequate gas exchange by the respiratory system)
Sinusitis (inflammation of sinus)
Tremor (trembling or shaking movements in one or more parts of your body)
Vomiting
Bone cancer metastatic
Metastases to bone (cancer spreads to bone)
Wheezing (a high-pitched whistling sound made while you breath)
Cardiomegaly (increased size of heart than normal)
Hepatic lesion

50-59:

Abdominal distension
Abdominal pain

60+:

Oedema peripheral (superficial swelling)
Arthralgia (joint pain)
Atrioventricular block complete (heart block complete)
Back injury
Blood cholesterol increased
Blood pressure fluctuation
Blood triglycerides increased
Bradycardia (abnormally slow heart action)
Breast tenderness
Cardiac murmur (an heart sound in valve abnormality)

What are the existing conditions these people have? *

Pain: 11 people, 50.00%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 6 people, 27.27%
Breast Cancer: 6 people, 27.27%
Nausea And Vomiting: 5 people, 22.73%
Intervertebral Disc Degeneration (spinal disc degeneration): 5 people, 22.73%
Glossitis (infection of tongue with soreness): 5 people, 22.73%
Dissociative Disorder: 5 people, 22.73%
Depression: 4 people, 18.18%
Stress And Anxiety: 3 people, 13.64%
Irritable Bowel Syndrome: 3 people, 13.64%

* Approximation only. Some reports may have incomplete information.

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