Montelukast sodium and Tirosint drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Montelukast sodium (montelukast sodium) and Tirosint (levothyroxine sodium). Common drug interactions include sarcoidosis among females and atrial fibrillation among males.

The phase IV clinical study analyzes what interactions people have when they take Montelukast sodium and Tirosint. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Montelukast sodium?

Montelukast sodium has active ingredients of montelukast sodium. It is often used in asthma. eHealthMe is studying from 26,093 Montelukast sodium users. Check the latest studies of Montelukast sodium.

What is Tirosint?

Tirosint has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 5,000 Tirosint users. Check the latest studies of Tirosint.



On Jul, 23, 2026

36 people who take Montelukast sodium and Tirosint together, and have interactions are studied.

Montelukast sodium and Tirosint drug interactions.

What are the common drug interactions of Montelukast Sodium and Tirosint, by gender? *:

female:

  1. Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands)
  2. Ulcer
  3. Vitreous detachment (a condition of the eye in which the vitreous humour separates from the retina)
  4. Arthralgia (joint pain)
  5. Asthenia (weakness)
  6. Depression
  7. Fatigue (feeling of tiredness)
  8. Weight increased
  9. Anaemia (lack of blood)
  10. Ankle fracture

male:

  1. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  2. Cardiac failure congestive
  3. Constipation
  4. Decreased appetite
  5. Pericardial effusion (fluid around the heart)
  6. Peripheral swelling

What are the common drug interactions of Montelukast Sodium and Tirosint, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Chronic kidney disease
  2. Anaemia (lack of blood)
  3. Angiotensin converting enzyme increased
  4. Ankle fracture
  5. Blood potassium decreased
  6. Cluster headache (one-sided head pain with tearing)
  7. Diastolic dysfunction
  8. Dry eye (lack of adequate tears)
  9. Dry mouth
  10. Epstein-barr virus infection

50-59:

  1. Crying
  2. Arthralgia (joint pain)
  3. Asthenia (weakness)
  4. Back pain
  5. Balance disorder
  6. Bradykinesia (decreased bodily movement. it is associated with basal ganglia diseases)
  7. Depression
  8. Fatigue (feeling of tiredness)
  9. Memory impairment
  10. Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

60+:

  1. Insomnia (sleeplessness)
  2. Sinusitis (inflammation of sinus)
  3. Pain
  4. Seasonal allergy (allergic condition due to certain season)
  5. Acute sinusitis
  6. Arthralgia (joint pain)
  7. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  8. Back injury
  9. Cardiac failure congestive
  10. Crying

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 15 people, 41.67%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 13 people, 36.11%
  3. Infection: 7 people, 19.44%
  4. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 7 people, 19.44%
  5. Cough: 7 people, 19.44%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 19.44%
  7. High Blood Pressure: 7 people, 19.44%
  8. Hyperlipidaemia (presence of excess lipids in the blood): 7 people, 19.44%
  9. Hypersensitivity: 7 people, 19.44%
  10. Eye Infection: 6 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Montelukast sodium and Tirosint:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Montelukast sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Tirosint:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Montelukast sodium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tirosint and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on montelukast sodium and levothyroxine sodium (the active ingredients of Montelukast sodium and Tirosint, respectively), and Montelukast sodium and Tirosint (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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