Morphine sulfate and Combivir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Morphine sulfate (morphine sulfate) and Combivir (lamivudine; zidovudine). Common drug interactions include anaphylactic shock among females and emotional distress among males.

The phase IV clinical study analyzes what interactions people have when they take Morphine sulfate and Combivir. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Morphine sulfate?

Morphine sulfate has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 87,261 Morphine sulfate users. Check the latest studies of Morphine sulfate.

What is Combivir?

Combivir has active ingredients of lamivudine; zidovudine. It is often used in hiv infection. eHealthMe is studying from 15,450 Combivir users. Check the latest studies of Combivir.



On Jul, 26, 2026

28 people who take Morphine sulfate and Combivir together, and have interactions are studied.

Morphine sulfate and Combivir drug interactions.

What are the common drug interactions of Morphine Sulfate and Combivir, by gender? *:

female:

  1. Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
  2. Anxiety
  3. Arthralgia (joint pain)
  4. Chordee (a condition in which the head of the penis curves downward or upward, at the junction of the head)
  5. Depression
  6. Drug withdrawal syndrome neonatal (prenatal nas is caused by discontinuation of drugs taken by the pregnant mother)
  7. Dyskinesia neonatal (abnormality or impairment of voluntary movement-in child)
  8. Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
  9. Foot fracture
  10. Gait disturbance

male:

  1. Emotional distress
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Rhinorrhoea (watery mucus discharge from the nose)
  4. Anaemia (lack of blood)
  5. Drug resistance (reduction in effectiveness of a drug)
  6. Hypersensitivity
  7. Influenza like illness
  8. Pyrexia (fever)
  9. Renal impairment (severely reduced kidney function)
  10. Viral infection

What are the common drug interactions of Morphine Sulfate and Combivir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Arthralgia (joint pain)
  3. Chronic kidney disease
  4. Emotional distress
  5. Hypersensitivity
  6. Influenza like illness
  7. Multiple injuries
  8. Myalgia (muscle pain)
  9. Pyrexia (fever)
  10. Renal failure (kidney dysfunction)

40-49:

  1. Chronic kidney disease
  2. Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
  3. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  4. Anxiety
  5. Bone pain
  6. Drug resistance (reduction in effectiveness of a drug)
  7. Emotional distress
  8. Gait disturbance
  9. Renal impairment (severely reduced kidney function)
  10. Bone density decreased

50-59:

  1. Anaemia (lack of blood)
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
  4. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  5. Drug level above therapeutic
  6. Foot fracture
  7. Gait disturbance
  8. Gamma-glutamyltransferase increased
  9. Gynaecomastia (enlargement of the gland tissue of the male breast)
  10. Hepatitis cholestatic (flow of bile from the liver is slowed or blocked)

60+:

n/a

What are the existing conditions these people have? *

  1. Hiv Infection: 16 people, 57.14%
  2. Nausea (feeling of having an urge to vomit): 5 people, 17.86%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 17.86%
  4. Bacterial Infection: 5 people, 17.86%
  5. Inflammation: 3 people, 10.71%
  6. Fungal Infection: 3 people, 10.71%
  7. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 3 people, 10.71%
  8. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 7.14%
  9. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 7.14%
  10. High Blood Cholesterol: 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Morphine sulfate and Combivir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Morphine sulfate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Combivir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Morphine sulfate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Combivir and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on morphine sulfate and lamivudine; zidovudine (the active ingredients of Morphine sulfate and Combivir, respectively), and Morphine sulfate and Combivir (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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