Morphine sulfate and Delsym drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Morphine sulfate (morphine sulfate) and Delsym (dextromethorphan polistirex). Common drug interactions include pulmonary oedema among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Morphine sulfate and Delsym. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Morphine sulfate?

Morphine sulfate has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 87,261 Morphine sulfate users. Check the latest studies of Morphine sulfate.

What is Delsym?

Delsym has active ingredients of dextromethorphan polistirex. It is often used in cough. eHealthMe is studying from 5,033 Delsym users. Check the latest studies of Delsym.



On Jul, 12, 2026

14 people who take Morphine sulfate and Delsym together, and have interactions are studied.

Morphine sulfate and Delsym drug interactions.

What are the common drug interactions of Morphine Sulfate and Delsym, by gender? *:

female:

  1. Pulmonary oedema (fluid accumulation in the lungs)
  2. Anxiety
  3. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  4. Pleuritic pain
  5. Pulmonary toxicity (side effects on the lungs)
  6. Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
  7. Drug hypersensitivity
  8. Acute respiratory failure
  9. Chronic kidney disease
  10. Interstitial lung disease

male:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Chronic kidney disease
  4. Death
  5. Emotional distress
  6. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)

What are the common drug interactions of Morphine Sulfate and Delsym, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Cardiac failure congestive
  2. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  3. Death
  4. Hospitalisation

40-49:

  1. Abdominal pain lower
  2. Abdominal pain upper
  3. Atelectasis (partial or complete collapse of the lung)
  4. Autonomic neuropathy (malfunction of the autonomic nervous system (ans))
  5. Bilirubin conjugated increased
  6. Blindness
  7. Blood albumin decreased
  8. Blood calcium decreased
  9. Blood carbon dioxide increased
  10. Blood cholesterol increased

50-59:

  1. Death
  2. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)

60+:

  1. Dyspnoea (difficult or laboured respiration)
  2. Hypoxia (low oxygen in tissues)
  3. Acute respiratory failure
  4. Chronic kidney disease
  5. Interstitial lung disease
  6. Ovarian cancer stage iv
  7. Pulmonary embolism (blockage of the main artery of the lung)
  8. Disease progression
  9. Drug hypersensitivity
  10. Malignant neoplasm progression (cancer tumour came back)

What are the existing conditions these people have? *

  1. Ovarian Cancer Recurrent (reoccurrence of ovary cancer): 3 people, 21.43%
  2. Ovarian Cancer Metastatic (cancer of ovary spreads to other organ or parts): 3 people, 21.43%
  3. Renal Cell Carcinoma (a kidney cancer): 1 person, 7.14%
  4. Ovarian Cancer (cancer of ovary): 1 person, 7.14%
  5. Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 1 person, 7.14%
  6. Hiv Infection: 1 person, 7.14%
  7. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Morphine sulfate and Delsym:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Morphine sulfate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Delsym:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Morphine sulfate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Delsym and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on morphine sulfate and dextromethorphan polistirex (the active ingredients of Morphine sulfate and Delsym, respectively), and Morphine sulfate and Delsym (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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