Morphine sulfate and Norepinephrine bitartrate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Morphine sulfate (morphine sulfate) and Norepinephrine bitartrate (norepinephrine bitartrate). Common drug interactions include fear among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Morphine sulfate and Norepinephrine bitartrate. It is created by eHealthMe based on reports of 81 people who take the same drugs from the FDA, and is updated regularly.

What is Morphine sulfate?

Morphine sulfate has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 87,262 Morphine sulfate users. Check the latest studies of Morphine sulfate.

What is Norepinephrine bitartrate?

Norepinephrine bitartrate has active ingredients of norepinephrine bitartrate. eHealthMe is studying from 2,370 Norepinephrine bitartrate users. Check the latest studies of Norepinephrine bitartrate.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

81 people who take Morphine sulfate and Norepinephrine bitartrate together, and have interactions are studied.

Morphine sulfate and Norepinephrine bitartrate drug interactions.

What are the common drug interactions of Morphine Sulfate and Norepinephrine Bitartrate, by gender? *:

female:

Fear
Injury
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Stress
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Death
Multi-organ failure (multisystem organ failure)
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Respiratory failure (inadequate gas exchange by the respiratory system)

male:

Pneumonia
Respiratory failure (inadequate gas exchange by the respiratory system)
Cardiac failure congestive
Renal failure acute (rapid kidney dysfunction)
Aspartate aminotransferase increased
Cardiogenic shock (inadequate circulation of blood)
Injury
Arrhythmia (irregular heartbeat)
Asthenia (weakness)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

What are the common drug interactions of Morphine Sulfate and Norepinephrine Bitartrate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Acute pulmonary oedema (sudden deposit of fluid in the lung))
Agitation (state of anxiety or nervous excitement)
Bradycardia (abnormally slow heart action)
Cardiac failure
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haemoglobin decreased
Hyperthermia (body temperature greatly above normal)
Oxygen saturation decreased
Pallor
Pleural effusion (water on the lungs)

10-19:

n/a

20-29:

Hypotension (abnormally low blood pressure)
Asthenia (weakness)
Atrioventricular block (heart block)
Bradycardia (abnormally slow heart action)
Brain death
Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Cardiac failure
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Contusion (a type of hematoma of tissue in which capillaries)
Dysuria (painful or difficult urination)

30-39:

Live birth
Maternal exposure during pregnancy (use of substance during pregnancy)
Premature baby
Anxiety
Dyspnoea (difficult or laboured respiration)
Clostridial infection (infectious conditions by clostridium bacteria)
Colitis (inflammation of colon)
Enteritis (inflammation of the small intestine)
Enterococcal infection
Normal newborn

40-49:

Injury
Renal failure (kidney dysfunction)
Multi-organ failure (multisystem organ failure)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Death
Emotional distress
Fear
Renal impairment (severely reduced kidney function)
Renal injury (kidney injury)

50-59:

Multi-organ failure (multisystem organ failure)
Sepsis (a severe blood infection that can lead to organ failure and death)
Thrombocytopenia (decrease of platelets in blood)
Anaemia (lack of blood)
Aortic thrombosis (formation of a blood clot inside aorta)
Arrhythmia (irregular heartbeat)
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Cardiac arrest

60+:

Pneumonia
Respiratory failure (inadequate gas exchange by the respiratory system)
Thrombocytopenia (decrease of platelets in blood)
Death
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diarrhoea
Nausea (feeling of having an urge to vomit)
Pyrexia (fever)
Troponin i increased
Anhedonia (inability to experience pleasure from activities usually found enjoyable)

What are the existing conditions these people have? *

High Blood Pressure: 13 people, 16.05%
Back Pain: 8 people, 9.88%
Thrombocytopenia (decrease of platelets in blood): 5 people, 6.17%
Epidural Anaesthesia: 5 people, 6.17%
Anaemia (lack of blood): 5 people, 6.17%

* Approximation only. Some reports may have incomplete information.

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