Morphine sulfate and Ontak drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Morphine sulfate (morphine sulfate) and Ontak (denileukin diftitox). Common drug interactions include disease progression among females and actinic keratosis among males.

The phase IV clinical study analyzes what interactions people have when they take Morphine sulfate and Ontak. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Morphine sulfate?

Morphine sulfate has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 87,261 Morphine sulfate users. Check the latest studies of Morphine sulfate.

What is Ontak?

Ontak has active ingredients of denileukin diftitox. eHealthMe is studying from 457 Ontak users. Check the latest studies of Ontak.



On Jul, 20, 2026

14 people who take Morphine sulfate and Ontak together, and have interactions are studied.

Morphine sulfate and Ontak drug interactions.

What are the common drug interactions of Morphine Sulfate and Ontak, by gender? *:

female:

  1. Disease progression
  2. Mycosis fungoides (lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin)
  3. Blood albumin decreased
  4. Capillary fragility increased
  5. Drug effect decreased
  6. Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)

male:

  1. Actinic keratosis (skin disease due to sun exposure)
  2. Erythema (redness of the skin)
  3. Blood albumin decreased
  4. Blood calcium decreased
  5. Confusional state
  6. Dyspnoea (difficult or laboured respiration)
  7. Somnolence (a state of near-sleep, a strong desire for sleep)
  8. Abasia (inability to walk)
  9. Death
  10. Decreased appetite

What are the common drug interactions of Morphine Sulfate and Ontak, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Blood bilirubin increased
  2. Engraftment syndrome (inflammatory condition during neutrophil recovery after hematopoietic stem cell transplantation)
  3. Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
  4. Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
  5. Nausea (feeling of having an urge to vomit)
  6. Skin disorder (skin disease)
  7. Streptococcal infection
  8. Transfusion reaction (a serious problem that occurs after a patient receives a transfusion of blood)
  9. Vomiting

40-49:

  1. General physical health deterioration (weak health status)
  2. Mycosis fungoides (lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin)
  3. Sunburn
  4. Acute respiratory failure
  5. Asthenia (weakness)
  6. Blood albumin decreased
  7. Blood calcium decreased
  8. Confusional state
  9. Dyspnoea (difficult or laboured respiration)
  10. Somnolence (a state of near-sleep, a strong desire for sleep)

50-59:

  1. Disease progression
  2. Mycosis fungoides (lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin)
  3. Blood albumin decreased
  4. Drug effect decreased

60+:

  1. Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)

What are the existing conditions these people have? *

  1. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 7 people, 50.00%
  2. Ovarian Cancer Metastatic (cancer of ovary spreads to other organ or parts): 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Morphine sulfate and Ontak:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Morphine sulfate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ontak:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Morphine sulfate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ontak and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on morphine sulfate and denileukin diftitox (the active ingredients of Morphine sulfate and Ontak, respectively), and Morphine sulfate and Ontak (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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