Morphine sulfate and Pepcid ac drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Morphine sulfate (morphine sulfate) and Pepcid ac (famotidine). Common drug interactions include pruritus among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Morphine sulfate and Pepcid ac. It is created by eHealthMe based on reports of 78 people who take the same drugs from the FDA, and is updated regularly.

What is Morphine sulfate?

Morphine sulfate has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 87,261 Morphine sulfate users. Check the latest studies of Morphine sulfate.

What is Pepcid ac?

Pepcid ac has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 9,573 Pepcid ac users. Check the latest studies of Pepcid ac.

On Jul, 24, 2026

78 people who take Morphine sulfate and Pepcid ac together, and have interactions are studied.

Morphine sulfate and Pepcid ac drug interactions.

What are the common drug interactions of Morphine Sulfate and Pepcid Ac, by gender? *:

female:

Pruritus (severe itching of the skin)
Urticaria (rash of round, red welts on the skin that itch intensely)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Fatigue (feeling of tiredness)
Haemoglobin decreased
Pneumonia
Renal injury (kidney injury)
Stomatitis (inflammation of mucous membrane of mouth)
Subdural haemorrhage (bleeding between the skull and the surface of the brain)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

male:

Renal failure (kidney dysfunction)
Infection
Lymphadenopathy (disease or enlargement of lymph nodes)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Metastases to bone (cancer spreads to bone)
Physical disability
Pleural effusion (water on the lungs)
Scar
Collapse of lung (functional breakdown of lung)
Hypertension (high blood pressure)

What are the common drug interactions of Morphine Sulfate and Pepcid Ac, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Abdominal pain
Pruritus (severe itching of the skin)
Urticaria (rash of round, red welts on the skin that itch intensely)
Hypotension (abnormally low blood pressure)
Oxygen saturation decreased
Vomiting

10-19:

n/a

20-29:

Death
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

30-39:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Abdominal pain upper
Cardiac aneurysm (a condition that can occur after a myocardial infarction due to the inadequate resistance of the new scar tissue to the systolic pressure)
Flushing (the warm, red condition of human skin)
Insomnia (sleeplessness)
Lymphocyte count decreased
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Pneumonia
Quadriplegia (a four limb paralysis)

40-49:

Chronic kidney disease
Acidosis (build-up of carbon dioxide in the blood)
Acute respiratory failure
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Cardiac disorder
Cervical radiculopathy (disturbance of nerve function that causes pain in the upper body)
Complex regional pain syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet))
Dyspnoea (difficult or laboured respiration)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Hypercapnia (too much smoke)

50-59:

Emotional distress
Haematuria (presence of blood in urine)
Infection
Injury
Intestinal resection
Lymphadenopathy (disease or enlargement of lymph nodes)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Metastases to bone (cancer spreads to bone)
Physical disability
Pleural effusion (water on the lungs)

60+:

Renal failure (kidney dysfunction)
Gait disturbance
Anxiety
Atelectasis (partial or complete collapse of the lung)
Balance disorder
Biliary dilatation
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Bone marrow oedema (inflammation that causes much than the needed fluid in a bone)
Bone pain
Carcinoid syndrome (syndrome includes flushing and diarrhoea, and, less frequently, heart failure and bronchoconstriction)

What are the existing conditions these people have? *

High Blood Pressure: 15 people, 19.23%
High Blood Cholesterol: 13 people, 16.67%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 10 people, 12.82%
Nausea (feeling of having an urge to vomit): 8 people, 10.26%
Diabetes: 7 people, 8.97%
Stress And Anxiety: 7 people, 8.97%
Indigestion: 6 people, 7.69%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 6 people, 7.69%
Depression: 6 people, 7.69%
Gastric Ulcer (stomach ulcer): 6 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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